Clone:
REA734
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Alternative names:
Leu-2, CD8a, MAL, p32, Cd8b1, LY3, Lyt3, P37, Ly-2

Specifications for CD8 antibodies

Overview

REA734 recognizes the human CD8 antigen, a cell-surface glycoprotein also known as Leu-2 or CD8a. CD8 is strongly expressed on human cytotoxic T cells and thymocytes as well as on a subset of NK cells. The CD8 antigen is a disulfide-linked dimer that exists either as a CD8a homodimer or as a CD8α/β heterodimer. CD8 acts as a co-receptor for the T cell receptor and binds to the MHC class I molecules. CD8 is involved in T cell development and activation of mature T cells. The CD8 antibody recognizes the α-subunit of the antigen. Additional information: Clone REA734 displays negligible binding to Fc receptors.

Alternative names

Leu-2, CD8a, MAL, p32, Cd8b1, LY3, Lyt3, P37, Ly-2

Detailed product information

Technical specifications

CloneREA734
Isotyperecombinant human IgG1
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenCD8
Alternative names of antigenLeu-2, CD8a, MAL, p32, Cd8b1, LY3, Lyt3, P37, Ly-2
Molecular mass of antigen [kDa]45
Distribution of antigenNK cells, T cells

Resources for CD8 antibodies

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.