Clone:
REA902
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC, MICS, IF, IHC, ICC, MC
Alternative names:
TFRC, T9, TfR, TfR1, Trfr, TR, p90

Extended validation for CD71 Antibody, anti-human, REAfinity™

Specificity

Epitope competition
In order to compare the epitope specificity of an antibody, the clone being used is compared with other known clones recognizing the same antigen in a competition assay.
Other clonesOverlap in epitope recognition with REA902
REAL444+
CY1G4+
OKT9++
M-A712++
T56/14+
MEM-75-
Cells were incubated with an excess of purified unconjugated CD71 (REA902) antibody followed by staining with fluorochrome-conjugated antibodies of other known clones against the same marker. Based on the fluorescence signal obtained, the clones were identified as recognizing completely overlapping (++), partially overlapping (+), or completely different epitopes (-) of the marker.

Specifications for CD71 Antibody, anti-human, REAfinity™

Overview

Clone REA902 recognizes the human CD71 antigen, a transferrin receptor, which is essential for iron transport into proliferating cells. CD71 is expressed on marrow stromal cells (MSCs) from bone marrow, on activated T and B lymphocytes, macrophages, and all proliferating cells. It is upregulated on lymphocytes during proliferative responses to antigens or mitogens but is not expressed on resting lymphocytes. CD71 is present on reticulocytes and erythroid progenitors in fetal liver, cord blood, and peripheral blood, yet it is lost as these differentiate to mature erythrocytes.
Additional information: Clone REA902 displays negligible binding to Fc receptors.

Alternative names

TFRC, T9, TfR, TfR1, Trfr, TR, p90

Detailed product information

Technical specifications

CloneREA902
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (S), human IgG1
Hosthuman cell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenCD71
Alternative names of antigenTFRC, T9, TfR, TfR1, Trfr, TR, p90
Molecular mass of antigen [kDa]85
Distribution of antigenB cells, endothelial cells, T cells, macrophages, ES and iPS cells, mesenchymal stem cells, brain, liver, B cells, endothelial cells, T cells, macrophages, ES and iPS cells, mesenchymal stem cells
Entrez Gene ID7037
RRIDAB_2726858, AB_2726893, AB_2726859, AB_2726894, AB_2726860, AB_2726897, AB_2726863, AB_2726898, AB_2726864, AB_2726899, AB_2726865, AB_2726895, AB_2726861, AB_2726896, AB_2726862, AB_2726891, AB_2726857, AB_2811653, AB_2726892

Resources for CD71 Antibody, anti-human, REAfinity™

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

References for CD71 Antibody, anti-human, REAfinity™

Publications

  1. Judd, W. et al. (1980) Novel surface antigen expressed on dividing cells but absent from nondividing cells. J. Exp. Med. 152: 1430-1435
  2. Phillips, J. H. et al. (1984) Natural killer cells activated in a human mixed lymphocyte response culture identified by expression of Leu-11 and class II histocompatibility antigens. J. Exp. Med. 159: 993-1008
  3. Loken, M. R. et al. (1987) Flow cytometric analysis of human bone marrow: I. Normal erythroid development. Blood 69: 255-263
  4. Pittenger, M. F. et al. (1999) Multilineage potential of adult human mesenchymal stem cells. Science 284: 143-147

Related products for
CD71 Antibody, anti-human, REAfinity™

3 products available

Seems like you are coming from USA!
Do you want to visit our website in your country?