Clone:
REA902
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC, MICS, IF, IHC, ICC, MC
Alternative names:
TFRC, T9, TfR, TfR1, Trfr, TR, p90

Specifications for CD71 Antibody, anti-human, REAfinity™

Overview

Clone REA902 recognizes the human CD71 antigen, a transferrin receptor, which is essential for iron transport into proliferating cells. CD71 is expressed on marrow stromal cells (MSCs) from bone marrow, on activated T and B lymphocytes, macrophages, and all proliferating cells. It is upregulated on lymphocytes during proliferative responses to antigens or mitogens but is not expressed on resting lymphocytes. CD71 is present on reticulocytes and erythroid progenitors in fetal liver, cord blood, and peripheral blood, yet it is lost as these differentiate to mature erythrocytes.
Additional information: Clone REA902 displays negligible binding to Fc receptors.

Alternative names

TFRC, T9, TfR, TfR1, Trfr, TR, p90

Detailed product information

Technical specifications

CloneREA902
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (S), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenCD71
Alternative names of antigenTFRC, T9, TfR, TfR1, Trfr, TR, p90
Molecular mass of antigen [kDa]85
Distribution of antigenB cells, endothelial cells, T cells, macrophages, ES and iPS cells, mesenchymal stem cells, brain, liver, B cells, endothelial cells, T cells, macrophages, ES and iPS cells, mesenchymal stem cells
Entrez Gene ID7037
RRIDAB_2726858, AB_2726893, AB_2726859, AB_2726894, AB_2726860, AB_2726897, AB_2726863, AB_2726898, AB_2726864, AB_2726899, AB_2726865, AB_2726895, AB_2726861, AB_2726896, AB_2726862, AB_2726891, AB_2726857, AB_2811653, AB_2726892

References for CD71 Antibody, anti-human, REAfinity™

Publications

  1. Judd, W. et al. (1980) Novel surface antigen expressed on dividing cells but absent from nondividing cells. J. Exp. Med. 152: 1430-1435
  2. Phillips, J. H. et al. (1984) Natural killer cells activated in a human mixed lymphocyte response culture identified by expression of Leu-11 and class II histocompatibility antigens. J. Exp. Med. 159: 993-1008
  3. Loken, M. R. et al. (1987) Flow cytometric analysis of human bone marrow: I. Normal erythroid development. Blood 69: 255-263
  4. Pittenger, M. F. et al. (1999) Multilineage potential of adult human mesenchymal stem cells. Science 284: 143-147

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