Clone:
Y2/51
Type of antibody:
Primary antibodies
Isotype:
mouse IgG1κ
Applications:
FC, MICS, IF, IHC
Alternative names:
ITGB3, BDPLT16, BDPLT2, GP3A, GPIIIa, GT

Extended validation for CD61 Antibody, anti-human

Specificity

Epitope competition
In order to compare the epitope specificity of an antibody, the clone being used is compared with other known clones recognizing the same antigen in a competition assay.
Other clonesOverlap in epitope recognition with Y2/51
VI-PL2++
RUU-PL7F12++
PM6/13++
REA761++
REAL328++
Cells were incubated with an excess of purified unconjugated CD61 (Y2/51) antibody followed by staining with fluorochrome-conjugated antibodies of other known clones against the same marker. Based on the fluorescence signal obtained, the clones were identified as recognizing completely overlapping (++), partially overlapping (+), or completely different epitopes (-) of the marker.

Specifications for CD61 Antibody, anti-human

Overview

The CD61 antibody recognizes the human CD61 antigen, which is also known as the integrin β3–subunit. CD61 associates with CD41 to form the heterodimeric GPIIb/GPIIIa complex that is present on human megakaryocytes and platelets and mediates cell adhesion processes. Together with CD51, CD61 forms the vitronectin receptor, which is present on platelets as well as on a variety of other cell types such as osteoclasts and endothelial vessel cells. The CD61 antibody specifically recognizes the integrin β3–chain of both heterodimeric complexes.

Alternative names

ITGB3, BDPLT16, BDPLT2, GP3A, GPIIIa, GT

Detailed product information

Technical specifications

CloneY2/51
Clonalitymonoclonal
Isotypemouse IgG1κ
Isotype controlIsotype Control Antibody, mouse IgG1
Hostmouse
Type of antibodyPrimary antibodies
Specieshuman, non-human primate
Cross-reactivity
rhesus monkey (
Macaca mulatta
)
AntigenCD61
Alternative names of antigenITGB3, BDPLT16, BDPLT2, GP3A, GPIIIa, GT
Molecular mass of antigen [kDa]84
Distribution of antigenmegakaryocytes, platelets, other, smooth muscle
Entrez Gene ID3690
RRIDAB_2727926, AB_2811493, AB_2811482, AB_2819705, AB_2819697, AB_2660492, AB_2660493, AB_2660498, AB_2660499, AB_2660502, AB_2727973

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CD61 Antibody, anti-human

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