Clone:
REA905
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
Intercellular adhesion molecule 3, CDw50, ICAM-R, ICAM3

Specifications for CD50 (ICAM-3) Antibody, anti-human, REAfinity™

Overview

Clone REA905 recognizes the human CD50 antigen, a type I transmembrane glycoprotein also known as intercellular adhesion molecule 3 (ICAM-3). As a member of the immunoglobulin superfamily, CD50 is closely related to ICAM-1 and consists of five immunoglobulin domains. It is expressed by leukocytes and is a ligand for CD11a (leukocyte adhesion LFA-1 protein). CD50 is also associated with the amino-terminal domain of ERM proteins and moesin and plays an essential role in primary immune responses.
Additional information: Clone REA905 displays negligible binding to Fc receptors.

Alternative names

Intercellular adhesion molecule 3, CDw50, ICAM-R, ICAM3

Detailed product information

Technical specifications

CloneREA905
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (S), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenCD50 (ICAM-3)
Alternative names of antigenIntercellular adhesion molecule 3, CDw50, ICAM-R, ICAM3
Molecular mass of antigen [kDa]56
Distribution of antigenleukocytes
Entrez Gene ID3385
RRIDAB_2726924, AB_2726983, AB_2726925, AB_2726984, AB_2726926, AB_2726988, AB_2726930, AB_2726989, AB_2726931, AB_2726985, AB_2726927, AB_2726986, AB_2726928, AB_2726987, AB_2726929, AB_2726981, AB_2726923, AB_2726982

References for CD50 (ICAM-3) Antibody, anti-human, REAfinity™

Publications

  1. de Fougerolles, A. R. et al. (1992) Intercellular adhesion molecule 3, a third adhesion counter-receptor for lymphocyte function-associated molecule 1 on resting lymphocytes. J. Exp. Med. 175(1): 185-190
  2. Serrador, J. M. et al. (2002) A novel serine-rich motif in the intercellular adhesion molecule 3 is critical for its ezrin/radixin/moesin-directed subcellular targeting. J. Biol. Chem. 277(12): 10400-10409

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