Clone:
DX5
Type of antibody:
Primary antibodies
Isotype:
rat IgMκ
Applications:
FC, MICS, IF, IHC
Alternative names:
Itga2, VLA-2α, α2 integrin, gpIa, DX5

Extended validation for CD49b Antibody, anti-mouse

Specificity

Epitope competition
In order to compare the epitope specificity of an antibody, the clone being used is compared with other known clones recognizing the same antigen in a competition assay.
Other clonesOverlap in epitope recognition with DX5
REA541++
HMα2-
REA981++
Cells were incubated with an excess of purified unconjugated CD49b (DX5) antibody followed by staining with fluorochrome-conjugated antibodies of other known clones against the same marker. Based on the fluorescence signal obtained, the clones were identified as recognizing completely overlapping (++), partially overlapping (+), or completely different epitopes (-) of the marker.

Specifications for CD49b Antibody, anti-mouse

Overview

Clone DX5 recognizes the mouse CD49b antigen, also known as α2 integrin or very late antigen-2, which is expressed on the vast majority of mouse natural killer (NK) cells and on a subset of NKT cells. CD49b is not as mouse strain-restricted as other NK cell markers, for example, NK1.1, and is expressed by most common inbred mouse strains.

Alternative names

Itga2, VLA-2α, α2 integrin, gpIa, DX5

Detailed product information

Technical specifications

CloneDX5
Clonalitymonoclonal
Isotyperat IgMκ
Isotype controlIsotype Control Antibody, rat IgM
Hostrat
Type of antibodyPrimary antibodies
Speciesmouse
AntigenCD49b
Alternative names of antigenItga2, VLA-2α, α2 integrin, gpIa, DX5
Molecular mass of antigen [kDa]126
Distribution of antigenB cells, endothelial cells, epithelial cells, fibroblasts, megakaryocytes, monocytes, NK cells, platelets, T cells, stem cells, lymphocytes, ES and iPS cells
Entrez Gene ID16398
RRIDAB_2751993, AB_2811545, AB_2660455, AB_2660456, AB_2660461, AB_2660462, AB_2660463, AB_2660464, AB_2660465, AB_2660466, AB_2752024

Related products for
CD49b Antibody, anti-mouse

3 products available

Seems like you are coming from USA!
Do you want to visit our website in your country?