Clone:
TS2/7
Type of antibody:
Primary antibodies
Isotype:
mouse IgG1κ
Applications:
FC, MICS, IF, IHC
Alternative names:
Itga1

Specifications for CD49a Antibody, anti-human

Overview

Clone TS2/7 recognizes the cell adhesion molecule human CD49a, which is a 200 kDa heterodimeric integrin receptor. CD49a, also known as integrin α1, interacts with integrin β1 (CD29) to form the VLA-1 complex which functions as a receptor for collagen and laminin-1. Integrin α1 plays a role in cell-cell adhesion and T cell proliferation and is expressed by activated T cells, NK cells, neuronal cells, fibroblasts, and mesenchymal cells.

Alternative names

Itga1

Detailed product information

Technical specifications

CloneTS2/7
Clonalitymonoclonal
Isotypemouse IgG1κ
Isotype controlIsotype Control Antibody, mouse IgG1
Hostmouse
Type of antibodyPrimary antibodies
Specieshuman
AntigenCD49a
Alternative names of antigenItga1
Molecular mass of antigen [kDa]128
Distribution of antigenfibroblasts, neurons, mesenchymal stem cells
Entrez Gene ID3672
RRIDAB_2658447, AB_2658448, AB_2658449, AB_2658450, AB_2658451, AB_2658452, AB_2658453, AB_2658454, AB_2658455, AB_2658456, AB_2658457, AB_2658458

References for CD49a Antibody, anti-human

Publications

  1. Boiret, N. et al. (2005) Characterization of nonexpanded mesenchymal progenitor cells from normal adult human bone marrow. Exp. Hematol. 33(2): 219-225
  2. Miettinen, M. et al. (1993) Distribution of VLA integrins in solid tumors. Emergence of tumor-type-related expression. Patterns in carcinomas and sarcomas. Am. J. Pathol. 142(4): 1009-1018
  3. Hemler, M. E. et al. (1985) Biochemical characterization of VLA-1 and VLA-2. Cell surface heterodimers on activated T cells. J. Biol. Chem. 260: 15246-15252

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CD49a Antibody, anti-human

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