Clone:
14.8
Type of antibody:
Primary antibodies
Isotype:
rat IgG2bκ
Applications:
FC, MICS, IF, IHC
Alternative names:
Ptprc, loc, Lyt-4, CD45, L-CA, Ly-5

Specifications for CD45RA Antibody, anti-mouse

Overview

The monoclonal antibody 14.8 recognizes the exon A-dependent epitope CD45RA, one of eight isoforms of the transmembrane glycoprotein CD45, which is a member of the PTP (Protein Tyrosine Phosphatase) family. CD45RA is expressed highly on B cells, weakly on CD8
+
T cells and nearly on all B-lineage cells but it is not detectable on hematopoietic stem cells or myeloid progenitors.

Alternative names

Ptprc, loc, Lyt-4, CD45, L-CA, Ly-5

Detailed product information

Technical specifications

Clone14.8
Clonalitymonoclonal
Isotyperat IgG2bκ
Isotype controlIsotype Control Antibody, rat IgG2b
Hostrat
Type of antibodyPrimary antibodies
Speciesmouse
AntigenCD45RA
Alternative names of antigenPtprc, loc, Lyt-4, CD45, L-CA, Ly-5
Molecular mass of antigen [kDa]135(calculated based on gene prediction)
Distribution of antigenB cells, NK cells, monocytes, T cells, thymocytes
Entrez Gene ID19264
RRIDAB_2658339, AB_2658340, AB_2658341, AB_2658342, AB_2658338

References for CD45RA Antibody, anti-mouse

Publications

  1. Hathcock, K. S. et al. (1992) Expression of variable exon A-, B-, and C-specific CD45 determinants on peripheral and thymic T cell populations. J. Immunol. 148: 19-28
  2. Inoue, T. et al. (1993)
    Distinction of mouse CD8
    +
    suppressor effector T cell clones from cytotoxic T cell clones by cytokine.
    J. Immunol. 150: 2121-2128
  3. Trowbridge, I. S. et al. (1991) CD45: a leukocyte-specific member of the protein tyrosine phosphatase family. J. Immunol. 1095(1): 46-56