Clone:
DF-T1
Type of antibody:
Primary antibodies
Isotype:
mouse IgG1κ
Applications:
FC, MICS, IF, IHC
Alternative names:
Spn, Leukosialin, GALGP, gpL115, Lsn

Specifications for CD43 Antibody, anti-human

Overview

Human CD43 (leukosialin) is a cell surface sialoglycoprotein that is involved in cell adhesion, differentiation and activation. The CD43 antigen is expressed on most leukocytes, i.e., T cells, NK cells, granulocytes, monocytes, and macrophages, on hematopoietic stem cells, and on platelets, but not on erythrocytes. Among B cells, CD43 is expressed on activated B cells and plasma cells but not on resting B cells, e.g., naive B cells. In bone marrow, CD43 is found on pro-B cells but is down-regulated during transition to the pre-B cell stage. CD43 is expressed on different myeloid and lymphoid tumors, including some B cell malignancies.

Alternative names

Spn, Leukosialin, GALGP, gpL115, Lsn

Detailed product information

Technical specifications

CloneDF-T1
Clonalitymonoclonal
Isotypemouse IgG1κ
Isotype controlIsotype Control Antibody, mouse IgG1
Hostmouse
Type of antibodyPrimary antibodies
Specieshuman, non-human primate
Cross-reactivity
rhesus monkey (
Macaca mulatta
)
,
olive baboon (
Papio anubis
)
AntigenCD43
Alternative names of antigenSpn, Leukosialin, GALGP, gpL115, Lsn
Molecular mass of antigen [kDa]38
Distribution of antigenB cells, granulocytes, macrophages, megakaryocytes, T cells, monocytes, NK cells, platelets, red blood cells, lymphocytes, stem cells, basophils, mesenchymal stem cells, neutrophils, plasma cells, thymocytes, bone marrow
Entrez Gene ID6693
RRIDAB_2819468, AB_2876908, AB_2876909, AB_2658125, AB_2658126, AB_2658127, AB_2658128, AB_2658131, AB_2658132, AB_2658133, AB_2658136, AB_2658137, AB_2658138, AB_2658139, AB_2819480

References for CD43 Antibody, anti-human

Publications

  1. Stross, W. P. et al. (1989) Molecule detected in formalin fixed tissue by antibodies MT1, DF-T1, and L60 (Leu-22) corresponds to CD43 antigen. J. Clin. Pathol. 42: 953-961

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