Clone:
8F9
Type of antibody:
Primary antibodies
Isotype:
mouse IgG2a
Applications:
FC
Alternative names:
DNGR-1, UNQ9341

Specifications for CD370 (CLEC9A) Antibody, anti-human

Overview

CD370 (CLEC9A), C-type lectin domain family 9 member A, is a type II transmembrane glycoproteine member of 241 amino acids with a predicted molecular mass of ~30 kDa. It is also known as DNGR-1 and is expressed on BDCA-3
+
myeloid dendritic cells from peripheral blood and lymphoid tissues. It acts as a receptor for necrotic cells and plays an important role in cross-presentation.

Alternative names

DNGR-1, UNQ9341

Detailed product information

Technical specifications

Clone8F9
Clonalitymonoclonal
Isotypemouse IgG2a
Isotype controlIsotype Control Antibody, mouse IgG2a
Hostmouse
Type of antibodyPrimary antibodies
Specieshuman
AntigenCD370 (CLEC9A)
Alternative names of antigenDNGR-1, UNQ9341
Molecular mass of antigen [kDa]27
Distribution of antigendendritic cells
Entrez Gene ID283420
RRIDAB_2657786, AB_2657789, AB_2657790, AB_2657791, AB_2657792, AB_2657793, AB_2657794, AB_2657795, AB_2657796

References for CD370 (CLEC9A) Antibody, anti-human

Publications

  1. Sancho, D. et al. (2008) Tumor therapy in mice via antigen targeting to a novel, DC-restricted C-type lectin. J. Clin. Invest. 118(6): 2098-2110
  2. Sancho, D. et al. (2009) Identification of a dendritic cell receptor that couples sensing of necrosis to immunity. Nature 458(7240): 899-903
  3. Poulin, L. F. et al. (2010)
    Characterization of human DNGR-1
    +
    BDCA3
    +
    leukocytes as putative equivalents of mouse CD8 alpha
    +
    dendritic cells.
    J. Exp. Med. 207(6): 1261-1271

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