Clone:
REA716
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
SRB1, CLA-1, CD36 antigen-like 1, SR-BI, SCARB1

Specifications for CD36L1 (SR-BI) Antibody, anti-human, REAfinity™

Overview

Clone REA716 recognizes the human CD36L1 antigen, an integral membrane protein, also known as SR-BI. CD36L1 is widly expressed, e.g. on macrophages, dendritic cells, adrenocortical cells, adipocytes, and trophoblastic cells. In hepatocytes, CD36L1 acts as a receptor for hepatitis C. It has been reported, that CD36L1 is able to bind HCV envelope glycoprotein E2, participate in entry of HCV pseudotype particles, and modulate HCV infection. Furthermore, CD36L1 is a receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, vitamin E, phosphatidylserine, and apoptotic cells.
Additional information: Clone REA716 displays negligible binding to Fc receptors.

Alternative names

SRB1, CLA-1, CD36 antigen-like 1, SR-BI, SCARB1

Detailed product information

Technical specifications

CloneREA716
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (S), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenCD36L1 (SR-BI)
Alternative names of antigenSRB1, CLA-1, CD36 antigen-like 1, SR-BI, SCARB1
Molecular mass of antigen [kDa]61
Distribution of antigendendritic cells, macrophages
Entrez Gene ID949
RRIDAB_2657767, AB_2657768, AB_2657769, AB_2657766

References for CD36L1 (SR-BI) Antibody, anti-human, REAfinity™

Publications

  1. Scarselli, E. et al. (2002) The human scavenger receptor class B type I is a novel candidate receptor for the hepatitis C virus. EMBO J. 21(19): 5017-5025
  2. Zeisel, M. B. et al. (2007) Scavenger receptor class B type I is a key host factor for hepatitis C virus infection required for an entry step closely linked to CD81. Hepatology 46(6): 1722-1731
  3. Valacchi, G. et al. (2011) Scavenger receptor class B type I: a multifunctional receptor. Ann. N. Y. Acad. Sci. 1229

Related products for
CD36L1 (SR-BI) Antibody, anti-human, REAfinity™

1 products available