Clone:
REA1184
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
GPIV, gpIIIb, PAS IV, PAS-4, FAT

Specifications for CD36 Antibody, anti-mouse, REAfinity™

Overview

Clone REA1184 recognizes the mouse CD36 antigen, which is a 88 kDa member of the class B scavenger receptor family. CD36 is not only expressed by platelets, but also by erythroid precursors, monocytes and macrophages, certain endothelial and specialized epithelial cells. On platelets, CD36 recognition of oxidized LDL contributes to their activation and provides a link between hyperlipidemia, oxidant stress, and the prothrombotic state. Cell-derived microparticles are also major ligands for CD36 and contribute to thrombus formation. Targeting CD36 is a promising avenue for the treatment of atheroinflammatory disorders.
Additional information: Clone REA1184 displays negligible binding to Fc receptors

Alternative names

GPIV, gpIIIb, PAS IV, PAS-4, FAT

Detailed product information

Technical specifications

CloneREA1184
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse
AntigenCD36
Alternative names of antigenGPIV, gpIIIb, PAS IV, PAS-4, FAT
Molecular mass of antigen [kDa]53
Distribution of antigenmacrophages
Entrez Gene ID12491
RRIDAB_2784159, AB_2784155, AB_2784154, AB_2784162, AB_2784161, AB_2784156, AB_2784164, AB_2784163, AB_2784158, AB_2784157, AB_2784160

References for CD36 Antibody, anti-mouse, REAfinity™

Publications

  1. Endemann, G. et al. (1993) CD36 is a receptor for oxidized low density lipoprotein. J. Biol. Chem. 268: 11811-11816

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CD36 Antibody, anti-mouse, REAfinity™

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