Type of antibody:
Primary antibodies, Recombinant antibodies
recombinant human IgG1
Alternative names:

Specifications for CD355 (CRTAM) Antibody, anti-mouse, REAfinity™


Clone REA882 recognizes the mouse CD355 antigen, also known as class I MHC-restricted T cell associated molecule (CRTAM). CD355 is a type I immunoglobulin-superfamily transmembrane receptor, which is expressed by activated CD8
T cells and NK cells, but it is also found on spleen, brain, and testis. CD355 recognizes nectin-like molecule 2 (Necl-2), a cell-surface protein that mediates epithelial cell junctions and interactions with other nectins and Necls. In association with Necl-2, CD355 promotes cytotoxicity of NK cells and IFN-γ secretion of CD8
T cells and NK cell–mediated rejection of tumors.
Additional information: Clone REA882 displays negligible binding to Fc receptors.

Alternative names


Detailed product information

Technical specifications

Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hosthuman cell line
Type of antibodyPrimary antibodies, Recombinant antibodies
AntigenCD355 (CRTAM)
Alternative names of antigenCRTAM
Molecular mass of antigen [kDa]42
Distribution of antigenT cells, NK cells
Entrez Gene ID54698
RRIDAB_2726629, AB_2726714, AB_2726630, AB_2726715, AB_2726631, AB_2726716, AB_2726632, AB_2726717, AB_2726712, AB_2726628, AB_2726713

Resources for CD355 (CRTAM) Antibody, anti-mouse, REAfinity™


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References for CD355 (CRTAM) Antibody, anti-mouse, REAfinity™


  1. Kennedy, J. et al. (2000) A molecular analysis of NKT cells: identification of a class-I restricted T cell-associated molecule (CRTAM). J. Leukoc. Biol. 67(5): 725-734
  2. Boles, K. S. et al. (2005)
    The tumor suppressor TSLC1/NECL-2 triggers NK-cell and CD8
    T-cell responses through the cell-surface receptor CRTAM.
    Blood 106: 779-786
  3. Yeh, J. H. et al. (2008) Regulation of a late phase of T cell polarity and effector functions by Crtam. Cell 132(5): 846-859

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