Clone:
REA1243
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
FGFR-4, FGFR4, TKF, FGF R4

Specifications for CD334 (FGFR4) Antibody, anti-human, REAfinity™

Overview

Clone REA1243 recognizes the human CD334 (FGFR4) antigen, known as Fibroblast growth factor receptor 4, which is a member of the fibroblast growth factor receptor family. This cell surface tyrosine kinase is a high affinity receptor for both acidic and basic fibroblast growth factor. The binding of CD334 with the acidic fibroblast growth factors FGF2, FGF6, and FGF8, FGF19 and GFG1 induces mitogenesis and differentiation. CD334 is expressed in adrenal, lung, kidney, liver, pancreas, intestine, striated muscle and spleen tissues of human fetuses. A soluble-form splice variant of FGFR 4 was identified in human gastrointestinal epithelial cells and cancer cells.
Additional information: Clone REA1243 displays negligible binding to Fc receptors.

Alternative names

FGFR-4, FGFR4, TKF, FGF R4

Detailed product information

Technical specifications

CloneREA1243
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (S), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenCD334 (FGFR4)
Alternative names of antigenFGFR-4, FGFR4, TKF, FGF R4
Molecular mass of antigen [kDa]86
Distribution of antigenepithelial cells, tumor cells, kidney, intestine, lung, liver, pancreas, spleen
Entrez Gene ID2264
RRIDAB_2876997, AB_2876934, AB_2876935, AB_2877027, AB_2877028, AB_2877007, AB_2877008, AB_2877017, AB_2877018, AB_2876946, AB_2876947, AB_2877003, AB_2877004, AB_2877023, AB_2877024, AB_2876958, AB_2876959, AB_2876996

References for CD334 (FGFR4) Antibody, anti-human, REAfinity™

Publications

  1. Partanan, J. et al. (1991) FGFR-4, a novel acidic fibroblast growth factor receptor with a distinct expression pattern. EMBO J. 10(6): 1347-1354
  2. Takaishi, S. et al. (2000) Identification of a novel alternative splicing of human FGF receptor 4: soluble-form splice variant expressed in human gastrointestinal epithelial cells. Biochem. Biophys. Res. Commun. 267(2): 658-662
  3. Ron, D. et al. (1993) Fibroblast growth factor receptor 4 is a high affinity receptor for both acidic and basic fibroblast growth factor but not for keratinocyte growth factor. J. Biol. Chem. 268(8): 5388-5394

Seems like you are coming from USA!
Do you want to visit our website in your country?