Clone:
REAL169
Type of antibody:
Releasable antibodies, Primary antibodies, Recombinant antibodies
Applications:
FC
Alternative names:
Siglec-3, p67, My9

Specifications for CD33 Antibody, anti-human,
REAlease
®

Overview

Clone REAL169 is an antibody fragment derived from the full CD33 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAlease Complex to bind markers with high avidity.
Clone REAL169 recognizes the human CD33 antigen, a 67 kDa glycoprotein belonging to the sialoadhesin superfamily. The CD33 antigen is highly expressed on human monocytes but weakly on granulocytes and some – but not all – myeloid dendritic cells. The CD33 antigen is also found on myeloid progenitor cells (CFU-GEMM, CFU GM, CFU-G, BFU-E) but is not expressed on lymphocytes, platelets, erythrocytes, or primitive hematopoietic stem cells.
The REAlease Kits consist of the respective fluorochrome-conjugated REAlease Complexes and the REAlease Support Kit for removal of the REAlease Complexes and optional relabeling with different fluorochrome-conjugated REAlease Complexes.

Alternative names

Siglec-3, p67, My9

Detailed product information

Technical specifications

CloneREAL169
Clonalitymonoclonal
Isotype controlControl Antibody
Hostcell line
Type of antibodyReleasable antibodies, Primary antibodies, Recombinant antibodies
Specieshuman
Cross-reactivitynon-human primate,
rhesus monkey (
Macaca mulatta
)
,
cynomolgus monkey (
Macaca fascicularis
)
AntigenCD33
Alternative names of antigenSiglec-3, p67, My9
Distribution of antigendendritic cells, granulocytes, Langerhans cells, macrophages, mast cells, monocytes, myeloid cells, NK cells, T cells, basophils, leukemia cells
RRIDAB_2752038, AB_2857672, AB_2857670, AB_2752050

Related products for
CD33 Antibody, anti-human,
REAlease
®

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