Clone:
REA1028
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC, MICS, IF, IHC
Alternative names:
PECAM1, CD31/EndoCAM, GPIIA', PECA1, PECAM-1, EndoCAM

Specifications for CD31 Antibody, anti-human, REAfinity™

Overview

Clone REA1028 recognizes the human CD31 antigen, a 120–140 kDa single-chain transmembrane glycoprotein, which is present on virtually all monocytes, platelets, and granulocytes. CD31 is also expressed by lymphocyte subsets. During maturation of CD4
+
T cells, the expression of CD31 changes: CD4
+
recent thymic emigrants (RTEs) express CD31 in contrast to central naive T cells. CD31 is highly expressed on endothelial cells, especially at their juncture, and is also known EndoCAM.
Additional information: Clone REA1028 displays negligible binding to Fc receptors.

Alternative names

PECAM1, CD31/EndoCAM, GPIIA', PECA1, PECAM-1, EndoCAM

Detailed product information

Technical specifications

CloneREA1028
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (S), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman, non-human primate
Cross-reactivity
rhesus monkey (
Macaca mulatta
)
AntigenCD31
Alternative names of antigenPECAM1, CD31/EndoCAM, GPIIA', PECA1, PECAM-1, EndoCAM
Molecular mass of antigen [kDa]80
Distribution of antigengranulocytes, monocytes, lymphocytes, platelets
Entrez Gene ID5175
RRIDAB_2727920, AB_2727885, AB_2727879, AB_2727916, AB_2727880, AB_2727917, AB_2727881, AB_2727882, AB_2727918, AB_2727883, AB_2727919, AB_2727884, AB_2727915

References for CD31 Antibody, anti-human, REAfinity™

Publications

  1. Stockinger, H. et al. (1990) Molecular characterization and functional analysis of the leukocyte surface protein CD31. J. Immunol. 145(11): 3889-3897
  2. Newman, P. J. et al. (1990) PECAM-1 (CD31) cloning and relation to adhesion molecules of the immunoglobulin gene superfamily. Science 247(4947): 1219-1222
  3. Kimmig, S. et al. (2002) Two subsets of naive T helper cells with distinct T cell receptor excision circle content in human adult peripheral blood. J. Exp. Med. 195(6): 789-794

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