Clone:
REA1129
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
CD300LF, CLM-1, IREM-1, IgSF13, LMIR3, NKIR, CLM

Specifications for CD300f (IREM-1) Antibody, anti-human, REAfinity™

Overview

Clone REA1129 recognizes the human CD300f antigen, also known as immune receptor expressed by myeloid cell 1 (IREM-1), which is a type I transmembrane glycoprotein member of the CD300 family. It is expressed on myeloid cells and in peripheral blood on monocytes and granulocytes. CD300f binds the p85α regulatory subunit of phosphoinositide 3-kinase (PI3K) and can enhance phagocytosis of apoptotic cells.
Additional information: Clone REA1129 displays negligible binding to Fc receptors.

Alternative names

CD300LF, CLM-1, IREM-1, IgSF13, LMIR3, NKIR, CLM

Detailed product information

Technical specifications

CloneREA1129
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (S), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenCD300f (IREM-1)
Alternative names of antigenCD300LF, CLM-1, IREM-1, IgSF13, LMIR3, NKIR, CLM
Molecular mass of antigen [kDa]30
Distribution of antigenmyeloid cells, granulocytes, monocytes
Entrez Gene ID146722
RRIDAB_2751718, AB_2751774, AB_2751719, AB_2751775, AB_2751720, AB_2751776, AB_2751721, AB_2751777, AB_2751722, AB_2751778, AB_2751723, AB_2751779, AB_2751724, AB_2751773

References for CD300f (IREM-1) Antibody, anti-human, REAfinity™

Publications

  1. Álvarez-Errico, D. et al. (2004) IREM-1 is a novel inhibitory receptor expressed by myeloid cells. Eur. J. Immunol. 34(12): 3690-3701
  2. Álvarez-Errico, D. et al. (2007) The IREM-1 (CD300f) inhibitory receptor associates with the p85α subunit of phosphoinositide 3-kinase. J. Immunol. 178: 808-816
  3. Choi, S. C. et al. (2011) Cutting edge: mouse CD300f (CMRF-35-like molecule-1) recognizes outer membrane-exposed phosphatidylserine and can promote phagocytosis. J. Immunol. 187(7): 3483-3487

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