Clone:
REA741
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
CLM-6, CMRF35-A1, CMRF-35, Immunoglobulin superfamily member 16, IgSF16

Specifications for CD300c Antibody, anti-human, REAfinity™

Overview

Clone REA741 recognizes the human CD300c antigen, a type I membrane protein, also known as CMRF-35, CLM-6, or CD300 antigen-like family member C. CD300c is expressed on monocytes, neutrophils, on subpopulations of T and B cells, and lymphocytic cell lines. CD300c plays a role in the regulation of TNF-α and IFN-α secretion in activated plasmacytoid dendritic cells (DCs) and is involved in proinflammatory cytokine production.
Additional information: Clone REA741 displays negligible binding to Fc receptors.

Alternative names

CLM-6, CMRF35-A1, CMRF-35, Immunoglobulin superfamily member 16, IgSF16

Detailed product information

Technical specifications

CloneREA741
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (S), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenCD300c
Alternative names of antigenCLM-6, CMRF35-A1, CMRF-35, Immunoglobulin superfamily member 16, IgSF16
Molecular mass of antigen [kDa]23
Distribution of antigenT cells, B cells, monocytes, neutrophils
Entrez Gene ID10871
RRIDAB_2657131, AB_2657132, AB_2657133, AB_2657134, AB_2657135, AB_2657136, AB_2657137, AB_2657130

References for CD300c Antibody, anti-human, REAfinity™

Publications

  1. Jackson, D. G. et al. (1992) Molecular cloning of a novel member of the immunoglobulin gene superfamily homologous to the polymeric immunoglobulin receptor. Eur. J. Immunol. 22(5): 1157-1163
  2. Clark, G. J. et al. (2000) The CMRF-35H gene structure predicts for an independently expressed member of an ITIM/ITAM pair of molecules localized to human chromosome 17. Tissue Antigens 55(2): 101-109

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