Clone:
11C1
Type of antibody:
Primary antibodies
Isotype:
mouse IgG1κ
Applications:
FC, MICS, IF, IHC
Alternative names:
TNFRSF13c, BR3, BAFFR, BROMIX, CD268, CVID4, prolixin

Specifications for CD268 Antibody, anti-human

Overview

The monoclonal antibody 11C1 reacts with the B cell–activating factor receptor (BAFF-R), also known as BAFF receptor 3 (BR3) or CD268. It is a 19 kDa type III transmembrane protein which belongs to the TNF receptor superfamily and is mainly expressed on B cells. BAFF-R plays an important role in B cell differentiation and promotes survival and activation of B cells.

Alternative names

TNFRSF13c, BR3, BAFFR, BROMIX, CD268, CVID4, prolixin

Detailed product information

Technical specifications

Clone11C1
Clonalitymonoclonal
Isotypemouse IgG1κ
Isotype controlIsotype Control Antibody, mouse IgG1
Hostmouse
Type of antibodyPrimary antibodies
Specieshuman
AntigenCD268
Alternative names of antigenTNFRSF13c, BR3, BAFFR, BROMIX, CD268, CVID4, prolixin
Molecular mass of antigen [kDa]19
Distribution of antigenB cells, T cells, spleen
Entrez Gene ID115650
RRIDAB_2656781, AB_2656782, AB_2656783, AB_2656784, AB_2656785, AB_2656786, AB_2656787, AB_2656780

References for CD268 Antibody, anti-human

Publications

  1. Kayagaki, N. et al. (2002) BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-κB2. Immunity 17(4): 515-524
  2. Thompson, J. S. et al. (2001) BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF. Science 293(5537): 2108-2111

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CD268 Antibody, anti-human

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