Clone:
DJR1
Type of antibody:
Primary antibodies
Isotype:
mouse IgG1κ
Applications:
FC
Alternative names:
TNFRSF10A, APO2, DR4, TRAILR1

Specifications for CD261 Antibody, anti-human

Overview

The DJR1 monoclonal antibody recognizes the human antigen CD261, which is also known as DR4 or TRAILR1. CD261 belongs to the TNF receptor family and is a receptor for TNFSF10/ trail. It promotes the activation of NF-κB and induces TRAIL-mediated apoptosis. CD261 is expressed on spleen, peripheral blood leukocytes, small intestine, and thymus, but also in K-562 erythroleukemia cells, MCF-7 breast carcinoma cells, and activated T cells.

Alternative names

TNFRSF10A, APO2, DR4, TRAILR1

Detailed product information

Technical specifications

CloneDJR1
Clonalitymonoclonal
Isotypemouse IgG1κ
Isotype controlIsotype Control Antibody, mouse IgG1
Hostmouse
Type of antibodyPrimary antibodies
Specieshuman
AntigenCD261
Alternative names of antigenTNFRSF10A, APO2, DR4, TRAILR1
Molecular mass of antigen [kDa]48
Distribution of antigenleukocytes
Entrez Gene ID8797
RRIDAB_2733107, AB_2656731, AB_2656732, AB_2656733, AB_2656734, AB_2656735, AB_2656736, AB_2656737, AB_2656738, AB_2656741, AB_2656742, AB_2733106

References for CD261 Antibody, anti-human

Publications

  1. Chaudhary, P. M. et al. (1997) Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappaB pathway. Immunity 7(6): 821-830
  2. Pan, G. et al. (1997) The receptor for the cytotoxic ligand TRAIL. Science 276(5309): 111-113

Related products for
CD261 Antibody, anti-human

3 products available

Seems like you are coming from USA!
Do you want to visit our website in your country?