Clone:
REA330
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
KEL, ECE3

Specifications for CD238 (KEL) Antibody, anti-human, REAfinity™

Overview

Clone REA330 recognizes the human CD238 antigen, a single-pass type II membrane protein also known as kell blood group glycoprotein (KEL). CD238 is a highly polymorphic antigen which links via a single disulfide bond to the XK membrane protein that carries the Kx antigen. It is expressed at high levels in erythrocytes and Sertoli cells, and at lower levels in skeletal muscle, in follicular dendritic cells, lymph nodes, and spleen. CD238 is also expressed in many adult and fetal nonerythroid tissues, including brain and bone marrow.
Additional information: Clone REA330 displays negligible binding to Fc receptors.

Alternative names

KEL, ECE3

Detailed product information

Technical specifications

CloneREA330
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (S), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenCD238 (KEL)
Alternative names of antigenKEL, ECE3
Molecular mass of antigen [kDa]83
Distribution of antigenred blood cells, dendritic cells, skeletal muscle, spleen
Entrez Gene ID3792
RRIDAB_2656513, AB_2656514, AB_2656515, AB_2656516, AB_2656517, AB_2656512

References for CD238 (KEL) Antibody, anti-human, REAfinity™

Publications

  1. Lee, S. et al. (1991) Molecular cloning and primary structure of Kell blood group protein. Proc. Natl. Acad. Sci. U.S.A. 88(14): 6353-6357
  2. Redman, C. M. et al. (1995) The Kell blood group system. Transfus. Clin. Biol. 2(4): 243-249
  3. Westhoff, C. M. et al. (2004) Review: the Kell, Duffy, and Kidd blood group systems. Immunohematology 20(1): 37-49

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