Clone:
REA1191
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
TSPAN7, A15, CCG-B7, DXS1692E, MRX58, MXS1, TALLA-1, TM4SF2, TM4SF2b

Specifications for CD231 (TALLA) Antibody, anti-human, REAfinity™

Overview

Clone REA1191 recognizes the human 150 kDa glycoprotein CD231 also known as T cell acute lymphoblastic leukemia specific antigen (TALLA), which is a member of the tetraspanin family. CD231 is expressed on T cell–type acute lymphoblastic leukemia (T-ALL) cells, skeletal muscle cells, brain, and spleen. It is reported that TALLA plays a role in integrin-mediated migration and can associate with phosphoinositide 4-kinase.
Additional information: Clone REA1191 displays negligible binding to Fc receptors.

Alternative names

TSPAN7, A15, CCG-B7, DXS1692E, MRX58, MXS1, TALLA-1, TM4SF2, TM4SF2b

Detailed product information

Technical specifications

CloneREA1191
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (S), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenCD231 (TALLA)
Alternative names of antigenTSPAN7, A15, CCG-B7, DXS1692E, MRX58, MXS1, TALLA-1, TM4SF2, TM4SF2b
Molecular mass of antigen [kDa]28
Distribution of antigenbrain, spleen, skeletal muscle
Entrez Gene ID7102
RRIDAB_2801828, AB_2801833, AB_2801829, AB_2801834, AB_2801830, AB_2801835, AB_2801831, AB_2801832

References for CD231 (TALLA) Antibody, anti-human, REAfinity™

Publications

  1. Hara, H. et al. (1987)
    Complete suppression of
    in vivo
    growth of human leukemia cells by specific immunotoxins: nude mouse models.
    Proc. Natl. Acad. Sci. U.S.A. 84: 3390-3394
  2. Seon, B. K. et al. (1983) Monoclonal antibody that defines a unique human T-cell leukemia antigen. Proc. Natl. Acad. Sci. U.S.A. 80: 845-849
  3. Matsuzaki, H. et al. (1987) Molecular nature of a cell membrane antigen specific for human T-cell acute lymphoblastic leukemia. Cancer Res. 47 : 4283-4286
  4. Yauch, R. L. et al. (2000) Specific interactions among transmembrane 4 superfamily (TM4SF) proteins and phosphoinositide 4-kinase. Biochem. J. 351: 629-637
  5. Takagi, S. et al. (1995) Identification of a highly specific surface marker of T-cell acute lymphoblastic leukemia and neuroblastoma as a new member of the transmembrane 4 superfamily. Int. J. Cancer 61(5): 706-715