Clone:
REA756
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
ICFC
Alternative names:
CD20L, HTM4

Specifications for CD20L (MS4A3) Antibody, anti-human, REAfinity™

Overview

Clone REA756 recognizes the human CD20L, an intracytoplasmic membrane protein, which is also known as Htm4 or MS4A3. It is present specifically in hematopoietic cells and tissues. CD20L functions as a hematopoietic modulator for the G1-S cell cycle transition. It binds to cyclin-dependent kinase inhibitor 3 (CDKN3/KAP) and modulates the level of phosphorylation of cyclin-dependent kinase 2 (CDK2).
Additional information: Clone REA756 displays negligible binding to Fc receptors.

Alternative names

CD20L, HTM4

Detailed product information

Technical specifications

CloneREA756
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (I), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenCD20L (MS4A3)
Alternative names of antigenCD20L, HTM4
Molecular mass of antigen [kDa]23
Distribution of antigenstem cells, hematopoietic stem and progenitor cells
Entrez Gene ID932
RRIDAB_2656273, AB_2656274, AB_2656275, AB_2656276, AB_2656277, AB_2656272

References for CD20L (MS4A3) Antibody, anti-human, REAfinity™

Publications

  1. Donato, J. L. et al. (2002) Human HTm4 is a hematopoietic cell cycle regulator. J. Clin. Invest. 109(1): 51-58
  2. Chinami, M. et al. (2005) Binding of HTm4 to cyclin-dependent kinase (Cdk)-associated phosphatase (KAP).Cdk2.cyclin A complex enhances the phosphatase activity of KAP, dissociates cyclin A, and facilitates KAP dephosphorylation of Cdk2. J. Biol. Chem. 280(17): 17235-17242

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