Clone:
REA850
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC, MICS, IF, IHC
Alternative names:
OX2R, CD200 receptor

Specifications for CD200R Antibody, anti-mouse, REAfinity™

Overview

Clone REA850 recognizes the mouse CD200R antigen, also known as orexin receptor 2 (OX2R). CD200R is a type I transmembrane glycoprotein expressed by cells of the myeloid lineage, e.g., monocytes, neutrophils, T cells, and mast cells. The interaction between CD200R and its ligand CD200 is involved in immune suppression and controls functions of monocytes and macrophages.
Additional information: Clone REA850 displays negligible binding to Fc receptors.

Alternative names

OX2R, CD200 receptor

Detailed product information

Technical specifications

CloneREA850
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse
AntigenCD200R
Alternative names of antigenOX2R, CD200 receptor
Molecular mass of antigen [kDa]33
Distribution of antigenmonocytes, T cells, mast cells
Entrez Gene ID57781
RRIDAB_2725846, AB_2725830, AB_2725847, AB_2725831, AB_2725848, AB_2725832, AB_2725849, AB_2725850, AB_2725844, AB_2725829, AB_2725845

References for CD200R Antibody, anti-mouse, REAfinity™

Publications

  1. Wright, G. J. et al. (2000) Lymphoid/neuronal cell surface OX2 glycoprotein recognizes a novel receptor on macrophages implicated in the control of their function. Immunity 13(2): 233-242
  2. Voulgaraki, D. et al. (2005) Multivalent recombinant proteins for probing functions of leucocyte surface proteins such as the CD200 receptor. Immunology 115(3): 337-346
  3. Jenmalm, M. C. et al. (2006) Regulation of myeloid cell function through the CD200 receptor. J. Immunol. 176(1): 191-199

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CD200R Antibody, anti-mouse, REAfinity™

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