Clone:
RM2-5
Type of antibody:
Primary antibodies, Functional-grade antibodies
Isotype:
rat IgG2bλ
Applications:
FA, FC, MICS, IF, IHC
Alternative names:
LFA-2, Ly-37

Specifications for CD2 Antibody, anti-mouse

Overview

The monoclonal antibody RM2-5 recognizes the type I transmembrane glycoprotein CD2, also known as LFA-2 or Ly-37. In mouse, CD2 is expressed on all lymphocytes except a subpopulation of intraepithelial T lymphocytes. It is a major receptor for CD48 and is involved in activation and differentiation of T cells. CD2-mediated cell-cell adhesion can be blocked by the RM2-5 antibody.

Alternative names

LFA-2, Ly-37

Detailed product information

Technical specifications

CloneRM2-5
Clonalitymonoclonal
Isotyperat IgG2bλ
Isotype controlIsotype Control Antibody, rat IgG2b
Hostrat
Type of antibodyPrimary antibodies, Functional-grade antibodies
Speciesmouse
AntigenCD2
Alternative names of antigenLFA-2, Ly-37
Molecular mass of antigen [kDa]36
Distribution of antigenB cells, T cells
Entrez Gene ID12481
RRIDAB_2661342, AB_2656049, AB_2656050, AB_2656051, AB_2656052, AB_2656053, AB_2656054, AB_2656055, AB_2656056, AB_2656057, AB_2656058

References for CD2 Antibody, anti-mouse

Publications

  1. Nakamura, T. et al. (1990) Relative contribution of CD2 and LFA-1 to murine T and natural killer cell functions. J. Immunol. 145: 3628-3634
  2. Yagita, H. et al. (1989) Monoclonal antibodies specific for murine CD2 reveal its presence on B as well as T cells. Proc. Natl. Acad. Sci. U.S.A. 86: 645-649
  3. Davis, S. J. and van der Merwe, P. A. (1996) The structure and ligand interactions of CD2: implications for T-cell function. Immunol. Today 17(4): 177-187

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