Clone:
REA959
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC, MICS, IF, IHC
Alternative names:
LFA-2, Ly-37

Specifications for CD2 Antibody, anti-mouse, REAfinity™

Overview

Clone REA959 recognizes the type I transmembrane glycoprotein CD2, also known as LFA-2 or Ly-37. In mouse, CD2 is expressed on all lymphocytes except a subpopulation of intraepithelial T lymphocytes. It is a major receptor for CD48 and is involved in activation and differentiation of T cells. CD2-mediated cell-cell adhesion can be blocked by REA959.
Additional information: Clone REA959 displays negligible binding to Fc receptors.

Alternative names

LFA-2, Ly-37

Detailed product information

Technical specifications

CloneREA959
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse
AntigenCD2
Alternative names of antigenLFA-2, Ly-37
Molecular mass of antigen [kDa]36
Distribution of antigenB cells, T cells
Entrez Gene ID12481
RRIDAB_2727243, AB_2727286, AB_2727244, AB_2727287, AB_2727245, AB_2727290, AB_2727248, AB_2727288, AB_2727246, AB_2727289, AB_2727247, AB_2727284, AB_2727242, AB_2727285

References for CD2 Antibody, anti-mouse, REAfinity™

Publications

  1. Yagita, H. et al. (1989) Monoclonal antibodies specific for murine CD2 reveal its presence on B as well as T cells. Proc. Natl. Acad. Sci. U.S.A. 86: 645-649
  2. Nakamura, T. et al. (1990) Relative contribution of CD2 and LFA-1 to murine T and natural killer cell functions. J. Immunol. 145: 3628-3634
  3. Davis, S. J. and van der Merwe, P. A. (1996) The structure and ligand interactions of CD2: implications for T-cell function. Immunol. Today 17(4): 177-187

Related products for
CD2 Antibody, anti-mouse, REAfinity™

2 products available

Seems like you are coming from USA!
Do you want to visit our website in your country?