Clone:
51.1
Type of antibody:
Primary antibodies
Isotype:
mouse IgG2bκ
Applications:
FC
Alternative names:
R3G1, R3, CD1a

Specifications for CD1d Antibody, anti-human

Overview

Clone 51.1 recognizes CD1d, a member of the CD1 family of MHC class I like glycoproteins involved in presenting lipid-based antigens to T cells. CD1d-restricted repertoire of T cells include NKT cells expressing invariant chain T cell receptors (TCRs), T cells with diverse TCRs, and naive like T cells with intermediate expression levels of the transcription factor PLZF. Expression of CD1d is found on the surface of many cells, including hepatocytes and professional antigen-presenting cells (APCs), including splenic dendritic cells (DCs), macrophages and B cells, intestinal epithelial cells, foreskin keratinocytes, penile urethral epithelial cells, and hepatocytes.

Alternative names

R3G1, R3, CD1a

Detailed product information

Technical specifications

Clone51.1
Clonalitymonoclonal
Isotypemouse IgG2bκ
Isotype controlIsotype Control Antibody, mouse IgG2b
Hostmouse
Type of antibodyPrimary antibodies
Specieshuman
AntigenCD1d
Alternative names of antigenR3G1, R3, CD1a
Molecular mass of antigen [kDa]36
Distribution of antigenB cells, T cells, dendritic cells
Entrez Gene ID912
RRIDAB_2656046, AB_2656047, AB_2656048, AB_2656045

References for CD1d Antibody, anti-human

Publications

  1. Constantinides, M. G. et al. (2011) A naive-like population of human CD1d-restricted T cells expressing intermediate levels of promyelocytic leukemia zinc finger. J. Immunol. 187: 309-315
  2. Exley, M. et al. (1997)
    Requirements for CD1d recognition by human invariant Vα24
    +
    CD4
    CD8
    T cells.
    J. Exp. Med. 186: 109-120
  3. Blumberg, R. S. et al. (1995) Structure and function of the CD1 family of MHC-like cell surface proteins. Immunol. Rev. 147: 5-29

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CD1d Antibody, anti-human

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