Clone:
REA942
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
CXC-R2, CXCR-2, IL-8R B, CXCR2, CMKAR2, Gpcr16, Il8rb

Specifications for CD182 (CXCR2) Antibody, anti-mouse, REAfinity™

Overview

Clone REA942 recognizes the mouse CD182 (CXCR2) antigen, which belongs to the class of chemokine receptors specific for CXC chemokines. Chemokine receptors are G-coupled protein receptors (GPCR) with seven-transmembrane domains and consist of an α-subunit and a βγ-complex. Binding of interleukin 8 (IL-8) to CD182 leads to the activation of neutrophil granulocytes. CD182 is also a ligand for CXCL3, GRO/MGSA, and NAP-2.
Additional information: Clone REA942 displays negligible binding to Fc receptors.

Alternative names

CXC-R2, CXCR-2, IL-8R B, CXCR2, CMKAR2, Gpcr16, Il8rb

Detailed product information

Technical specifications

CloneREA942
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse
AntigenCD182 (CXCR2)
Alternative names of antigenCXC-R2, CXCR-2, IL-8R B, CXCR2, CMKAR2, Gpcr16, Il8rb
Molecular mass of antigen [kDa]40
Distribution of antigendendritic cells, granulocytes, macrophages, T cells, basophils, eosinophils, neutrophils
Entrez Gene ID12765
RRIDAB_2727132, AB_2727078, AB_2727133, AB_2727079, AB_2727136, AB_2727081, AB_2727134, AB_2727080, AB_2727135

References for CD182 (CXCR2) Antibody, anti-mouse, REAfinity™

Publications

  1. Bozic, C. R. et al. (1994) The murine interleukin 8 type B receptor homologue and its ligands. Expression and biological characterization. J. Biol. Chem. 269(47): 29355-29358
  2. Nolan, K. F. et al. (2004) IL-10-conditioned dendritic cells, decommissioned for recruitment of adaptive immunity, elicit innate inflammatory gene products in response to danger signals. J. Immunol. 172(4): 2201-2209

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