Clone:
REAL445
Type of antibody:
Releasable antibodies, Primary antibodies, Recombinant antibodies
Applications:
FC
Alternative names:
LY64, Ly78, RP105

Specifications for CD180 (RP105) Antibody, anti-human,
REAlease
®

Overview

Clone REAL445 is an antibody fragment derived from the full CD180 (RP105) antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAlease Complex to bind markers with high avidity.
Clone REAL445 recognizes the human CD180 antigen, also known as RP105, which is a 105 kDa type 1 transmembrane protein of the toll-like receptor (TLR) family. The extracellular domain of CD180 is associated with MD-1, which forms the cell surface complex RP105/MD-1. Together with TLR4, it mediates B cell recognition and signaling of LPS. RP105 is expressed on mature B cells in mantle zones as well as on monocytes, macrophages, and dendritic cells.
The REAlease Kits consist of the respective fluorochrome-conjugated REAlease Complexes and the REAlease Support Kit for removal of the REAlease Complexes and optional relabeling with different fluorochrome-conjugated REAlease Complexes.

Alternative names

LY64, Ly78, RP105

Detailed product information

Technical specifications

CloneREAL445
Clonalitymonoclonal
Isotype controlControl Antibody
Hostcell line
Type of antibodyReleasable antibodies, Primary antibodies, Recombinant antibodies
Specieshuman
AntigenCD180 (RP105)
Alternative names of antigenLY64, Ly78, RP105
Distribution of antigenB cells, dendritic cells, monocytes, macrophages, mature B cells
RRIDAB_2819388, AB_2819390

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