Clone:
REA1066
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
lambda-5, IGLL1, IGL1

Specifications for CD179b Antibody, anti-human, REAfinity™

Overview

Clone REA1066 recognizes the CD179b antigen-like family member B, also known as immunoglobulin lambda like polypeptide (IGLL1). CD179b is expressed on pro–B and pre–B cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the pro–B cell to the pre–B cell stage, allelic exclusion at the Ig heavy chain gene locus, and support of Ig light chain gene rearrangements. The gene encoding for CD179b, as a B cell receptor, belongs to the immunoglobulin gene superfamily.
Additional information: Clone REA1066 displays negligible binding to Fc receptors.

Alternative names

lambda-5, IGLL1, IGL1

Detailed product information

Technical specifications

CloneREA1066
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (S), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman, non-human primate
Cross-reactivity
rhesus monkey (
Macaca mulatta
)
AntigenCD179b
Alternative names of antigenlambda-5, IGLL1, IGL1
Molecular mass of antigen [kDa]23
Distribution of antigenB cells, pre B cells, pro B cells
Entrez Gene ID3543
RRIDAB_2733777, AB_2733778, AB_2733349, AB_2733350, AB_2732964, AB_2732965, AB_2734008, AB_2734009, AB_2733506, AB_2733507

References for CD179b Antibody, anti-human, REAfinity™

Publications

  1. Hollis, G. F. et al. (1989) Immunoglobulin lambda light-chain-related genes 14.1 and 16.1 are expressed in pre-B cells and may encode the human immunoglobulin omega light-chain protein. Proc. Natl. Acad. Sci. U.S.A. 86(14): 5552-5556
  2. Bankovich, A. J. et al. (2007) Structural insight into pre-B cell receptor function. Science 316(5822): 291-294

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