CD154 Antibody, anti-mouse
Clone:
MR1
Type of antibody:
Primary antibodies
Isotype:
hamster IgG3κ
Applications:
FC, ICFC
Alternative names:
CD40LG, CD40L, HIGM1, IGM, IMD3, Ly-62, T-BAM, TRAP, TNFSF5, gp39

Specifications for CD154 Antibody, anti-mouse

Overview

Clone MR1 specifically recognizes the mouse CD154 antigen, a 39 kDa transmembrane glycoprotein also known as CD40L, gp39, T-BAM, TRAP, or Ly-62. CD154 is transiently up-regulated on activated CD4
+
T cells and plays an important role as a costimulatory molecule in T cell/antigen-presenting cell interactions through ligation of CD40. The antibody has been shown to block the activation of antigen-presenting cells by T helper cells
in vitro
. Due to its transient expression within hours after activation, CD154 can be used as a marker for activated antigen-specific CD4
+
T cells. Adding a CD40-blocking antibody during the stimulation of cell suspensions prevents the down-regulation of CD154. Blocking of CD40 is not required for intracellular detection of CD154 expression or if a pure population of enriched T cells is used.

Alternative names

CD40LG, CD40L, HIGM1, IGM, IMD3, Ly-62, T-BAM, TRAP, TNFSF5, gp39

Detailed product information

Technical specifications

CloneMR1
Clonalitymonoclonal
Isotypehamster IgG3κ
Hosthamster
Type of antibodyPrimary antibodies
Speciesmouse
AntigenCD154
Alternative names of antigenCD40LG, CD40L, HIGM1, IGM, IMD3, Ly-62, T-BAM, TRAP, TNFSF5, gp39
Molecular mass of antigen [kDa]29
Distribution of antigendendritic cells, macrophages, mast cells, monocytes, NK cells, T cells, lymphocytes, basophils
Entrez Gene ID21947
RRIDAB_2661125, AB_2661126, AB_2661127, AB_2661128, AB_2661124

Resources for CD154 Antibody, anti-mouse

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

Related products for
CD154 Antibody, anti-mouse

1 products available
130-093-129

CD154 Enrichment and Detection Kit (PE), mouse

The CD154 Enrichment and Detection Kit is designed for the easy identification and enrichment of ...

Seems like you are coming from USA!
Do you want to visit our website in your country?

Copyright © 2023 Miltenyi Biotec and/or its affiliates. All rights reserved.