Name: CD153 Antibody, anti-mouse
Availability: InStock

Flow cytometry

Conjugate:	APC
Recommended dilution:	1:10
Remark:	The antibody is suited for staining of formaldehyde-fixed cells.
Tested:	QC tested
Products used:	130-102-522

Functional assay

Conjugate:	pure-functional grade
Tested:	during development
Products used:	130-097-618
Type of functional assay:	blocking of receptor-ligand binding

Specifications for CD153 Antibody, anti-mouse

Overview

The monoclonal antibody RM153 reacts with mouse CD153 (CD30 ligand), a 40 kDa type II membrane protein belonging to the NGF/TNF superfamily. It is expressed by activated CD4

⁺

and CD8

⁺

T cells. The interaction between CD30 and CD153 enhance the proliferation of stimulated T cells. In the presence of the RM153 antibody this effect is blocked.

In vivo

treatment with this antibody is reported to inhibit or delay immune reactions.

Alternative names

TNFSF8, CD30LG, CD30L

Detailed product information

Technical specifications

Clone	RM153
Clonality	monoclonal
Isotype	rat IgG2bκ
Isotype control	Isotype Control Antibody, rat IgG2b
Host	rat
Type of antibody	Primary antibodies, Functional-grade antibodies
Species	mouse
Antigen	CD153
Alternative names of antigen	TNFSF8, CD30LG, CD30L
Molecular mass of antigen [kDa]	27
Distribution of antigen	B cells, granulocytes, macrophages, monocytes, eosinophils, neutrophils
Entrez Gene ID	21949
RRID	AB_2655257, AB_2655258, AB_2655256, AB_2655255

References for CD153 Antibody, anti-mouse

Publications

Akiba, H. et al. (1999) CD28-independent costimulation of T cells by OX40 ligand and CD70 on activated B cells. J. Immunol. 162(12): 7058-7066
Kjaergaard, J. et al. (2001) Augmentation versus inhibition: effects of conjunctional OX-40 receptor monoclonal antibody and IL-2 treatment on adoptive immunotherapy of advanced tumor. J. Immunol. 167: 6669-6677
al-Shamkhani, A. et al. (1996) OX40 is differentially expressed on activated rat and mouse T cells and is the sole receptor for the OX40 ligand. Eur. J. Immunol. 26(8): 1695-1699

Applications

Specifications

Specifications for CD153 Antibody, anti-mouse

Overview

The monoclonal antibody RM153 reacts with mouse CD153 (CD30 ligand), a 40 kDa type II membrane protein belonging to the NGF/TNF superfamily. It is expressed by activated CD4

⁺

and CD8

⁺

T cells. The interaction between CD30 and CD153 enhance the proliferation of stimulated T cells. In the presence of the RM153 antibody this effect is blocked.

In vivo

treatment with this antibody is reported to inhibit or delay immune reactions.

Alternative names

TNFSF8, CD30LG, CD30L

Detailed product information

Technical specifications

Clone	RM153
Clonality	monoclonal
Isotype	rat IgG2bκ
Isotype control	Isotype Control Antibody, rat IgG2b
Host	rat
Type of antibody	Primary antibodies, Functional-grade antibodies
Species	mouse
Antigen	CD153
Alternative names of antigen	TNFSF8, CD30LG, CD30L
Molecular mass of antigen [kDa]	27
Distribution of antigen	B cells, granulocytes, macrophages, monocytes, eosinophils, neutrophils
Entrez Gene ID	21949
RRID	AB_2655257, AB_2655258, AB_2655256, AB_2655255

References

References for CD153 Antibody, anti-mouse

Publications

Akiba, H. et al. (1999) CD28-independent costimulation of T cells by OX40 ligand and CD70 on activated B cells. J. Immunol. 162(12): 7058-7066
Kjaergaard, J. et al. (2001) Augmentation versus inhibition: effects of conjunctional OX-40 receptor monoclonal antibody and IL-2 treatment on adoptive immunotherapy of advanced tumor. J. Immunol. 167: 6669-6677
al-Shamkhani, A. et al. (1996) OX40 is differentially expressed on activated rat and mouse T cells and is the sole receptor for the OX40 ligand. Eur. J. Immunol. 26(8): 1695-1699

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CD153 Antibody, anti-mouse

CD153 Antibody, anti-mouse

Flow cytometry

Functional assay

Specifications for CD153 Antibody, anti-mouse

Overview

Alternative names

Detailed product information

Technical specifications

References for CD153 Antibody, anti-mouse

Publications

Specifications for CD153 Antibody, anti-mouse

Overview

Alternative names

Detailed product information

Technical specifications

References for CD153 Antibody, anti-mouse

Publications

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