Clone:
REA151
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
SLAMF1, CDw150, SLAM, IPO3

Specifications for CD150 (SLAM) Antibody, anti-human, REAfinity™

Overview

Clone REA151 recognizes CD150, a 70 kDa cell surface glycoprotein also known as SLAM, and belongs to the Ig superfamily. It acts as a self ligand. Expression of CD150 is found on B cells, dendritic cells, and activated/memory T cells and it is involved in functions such as stimulation, proliferation, and inhibition of apoptosis of B cells, stimulation and IFN-γ production in Tʜ1 T cell clones. CD150 has been identified as the second receptor for measles virus.
Additional information: Clone REA151 displays negligible binding to Fc receptors.

Alternative names

SLAMF1, CDw150, SLAM, IPO3

Detailed product information

Technical specifications

CloneREA151
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (S), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenCD150 (SLAM)
Alternative names of antigenSLAMF1, CDw150, SLAM, IPO3
Molecular mass of antigen [kDa]35
Distribution of antigenB cells, dendritic cells, T cells
Entrez Gene ID6504
RRIDAB_2876993, AB_2655216, AB_2655217, AB_2655218, AB_2655219, AB_2655220, AB_2655221, AB_2876992

References for CD150 (SLAM) Antibody, anti-human, REAfinity™

Publications

  1. Howie, D. et al. (2002) Molecular dissection of the signaling and costimulatory functions of CD150 (SLAM): CD150/SAP binding and CD150-mediated costimulation. Blood 99: 957-965
  2. Wang, N. et al. (2001) CD150 is a member of a family of genes that encode glycoproteins on the surface of hematopoietic cells. Immunogenetics 53(5): 382-394
  3. Welstead, G. G. et al. (2004) Mechanism of CD150 (SLAM) down regulation from the host cell surface by measles virus hemagglutinin protein. J. Virol. 78: 9666 -9674

Related products for
CD150 (SLAM) Antibody, anti-human, REAfinity™

3 products available

Seems like you are coming from USA!
Do you want to visit our website in your country?