Clone:
REA204
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
PTPRJ, DEP1, HPTPeta, R-PTP-ETA, SCC1

Specifications for CD148 Antibody, anti-human, REAfinity™

Overview

Clone REA204 recognizes CD148, a receptor type protein tyrosine phosphatase (PTP) belonging to the type III family of PTPs. CD148 is characterized by an extracellular domain with eight fibronectin type III repeats, a trans-membrane region, and a single cytosolic catalytic domain. Expression of CD148 is found on mature thymocytes, peripheral T cells, B cells, NK cells, granulocytes, macrophages, DC subpopulations, epithelial and endothelial cells, and fibroblasts. An upregulated expression of CD148 on human peripheral T cells is observed upon TCR stimulation. CD148 via regulating the phosphorylation status of substrates such as PDGFR, p120 catenin (CTND1), and SRC kinase, plays vital role in many cellular functions.
Additional information: Clone REA204 displays negligible binding to Fc receptors.

Alternative names

PTPRJ, DEP1, HPTPeta, R-PTP-ETA, SCC1

Detailed product information

Technical specifications

CloneREA204
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (S), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenCD148
Alternative names of antigenPTPRJ, DEP1, HPTPeta, R-PTP-ETA, SCC1
RRIDAB_2655203, AB_2655204, AB_2655205, AB_2655206, AB_2655207, AB_2655208, AB_2655209, AB_2655210, AB_2655211, AB_2655212, AB_2655213, AB_2655202

References for CD148 Antibody, anti-human, REAfinity™

Publications

  1. Tangye, S. G. et al. (1998) CD148: A receptor-type protein tyrosine phosphatase involved in the regulation of human T cell activation. J. Immunol. 161: 3249-3255
  2. de la Fuente-García, M. A. et al. (1998) CD148 is a membrane protein tyrosine phosphatase present in all hematopoietic lineages and is involved in signal transduction on lymphocytes. Blood 91: 2800-2809

Related products for
CD148 Antibody, anti-human, REAfinity™

3 products available

Seems like you are coming from USA!
Do you want to visit our website in your country?