Clone:
APB5
Type of antibody:
Primary antibodies
Isotype:
rat IgG2aκ
Applications:
FC, MICS, IF, IHC
Alternative names:
PDGFRB, PDGFR-1, Pdgfr, PDGF-Rβ

Specifications for CD140b Antibody, anti-mouse

Overview

Clone APB5 reacts with the transmembrane glycoprotein CD140b, the β-chain of the platelet-derived growth factor receptor (PDGFR). The two isoforms of the receptor can form homodimers (α/α or β/β) or heterodimers (α/β). Receptor dimerization and transphosphorylation at tyrosine residues activates the intracellular kinase activity. CD140b has been reported to be broadly expressed in embryonic tissue, mostly in cells of mesodermal origin in adult tissue. Expression of CD140a is associated with various malignancies.

Alternative names

PDGFRB, PDGFR-1, Pdgfr, PDGF-Rβ

Detailed product information

Technical specifications

CloneAPB5
Clonalitymonoclonal
Isotyperat IgG2aκ
Isotype controlIsotype Control Antibody, rat IgG2a
Hostrat
Type of antibodyPrimary antibodies
Speciesmouse
AntigenCD140b
Alternative names of antigenPDGFRB, PDGFR-1, Pdgfr, PDGF-Rβ
Molecular mass of antigen [kDa]120
Distribution of antigenendothelial cells, stem cells, mesenchymal stem cells
Entrez Gene ID18596
RRIDAB_2660643, AB_2660644, AB_2660645, AB_2660646, AB_2660647, AB_2660648, AB_2733763