Clone:
REA599
Type of antibody:
Recombinant antibodies, Primary antibodies
Isotype:
recombinant human IgG1
Alternative names:
LPS R

Specifications for CD14 antibodies

Overview

REA599 recognizes the human CD14 antigen. CD14 is part of the functional heteromeric LPS receptor complex comprised of at least CD14, TLR4, and MD-2. It up-regulates cell surface molecules, including adhesion molecules. CD14 is strongly expressed on most human monocytes and macrophages in peripheral blood, other bodily fluids, and in various tissues, such as lymph nodes and spleen. CD14 is weakly expressed on subpopulations of human neutrophils and myeloid dendritic cells. Additional information: Clone REA599 displays negligible binding to Fc receptors.

Applications

Reagent can be used for immunophenotyping by flow cytometry. Abnormal numbers of cells expressing this antigen or aberrant expression levels of the antigen can be expected in some disease states. It is important to understand the normal expression pattern for this antigen and its relationship to expression of other relevant antigens in order to perform appropriate analysis.
Expression of CD14 may be used as aid to diagnostic in the characterization of samples from individuals suspected with hematologic neoplasia.

Alternative names

LPS R

Detailed product information

Technical specifications

CloneREA599
Isotyperecombinant human IgG1
Type of antibodyRecombinant antibodies, Primary antibodies
Specieshuman
AntigenCD14
Alternative names of antigenLPS R
Molecular mass of antigen [kDa]37
Distribution of antigenB cells, dendritic cells, epithelial cells, granulocytes, Langerhans cells, macrophages, monocytes, osteoclasts, Langerhans cells, plasma cells

Resources for CD14 antibodies

Certificates

Please follow this
link
to download the Certificate of Conformity (CoC) by lot number.

Seems like you are coming from USA!
Do you want to visit our website in your country?