Type of antibody:
Releasable antibodies, Primary antibodies, Recombinant antibodies
Alternative names:
integrin αM, Mac-1 α, Integrin alpha-M, CR3A

Specifications for CD11b Antibody, anti-human,


Clone REAL744 is an antibody fragment derived from the full CD11b antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAlease Complex to bind markers with high avidity.
Clone REAL744 recognizes the human CD11b antigen (Mac-1 α; integrin αM chain), which is part of the CD11b/CD18 heterodimer (Mac-1 α, Mβ2 integrin), also known as the C3 complement receptor. It functions as a receptor for complement (C3bi), fibrinogen, or clotting factor X. In humans, CD11b is strongly expressed on myeloid cells and weakly expressed on NK cells and some activated lymphocytes as well as on microglia in the brain.
The REAlease Kits consist of the respective fluorochrome-conjugated REAlease Complexes and the REAlease Support Kit for removal of the REAlease Complexes and optional relabeling with different fluorochrome-conjugated REAlease Complexes.

Alternative names

integrin αM, Mac-1 α, Integrin alpha-M, CR3A

Detailed product information

Technical specifications

Isotype controlControl Antibody
Hostcell line
Type of antibodyReleasable antibodies, Primary antibodies, Recombinant antibodies
Alternative names of antigenintegrin αM, Mac-1 α, Integrin alpha-M, CR3A
Distribution of antigenmyeloid cells, NK cells, microglia, lymphocytes, brain

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