Clone:
REA596
Type of antibody:
Recombinant antibodies, Primary antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
ITGAL, LFA-1, ITGA

Specifications for CD11a Antibody, anti-rat, REAfinity™

Overview

Clone REA596 recognizes the rat CD11a antigen, a single-pass type I membrane protein, also known as integrin α-L (ITGAL). Integrins are heterodimeric adhesion molecules comprised of α- and β-subunits that participate in immune cell interactions as well as in immune cell–extracellular matrix interactions. CD11a combines with CD18 (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes.
Additional information: Clone REA596 displays negligible binding to Fc receptors.

Alternative names

ITGAL, LFA-1, ITGA

Detailed product information

Technical specifications

CloneREA596
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyRecombinant antibodies, Primary antibodies
Speciesrat
AntigenCD11a
Alternative names of antigenITGAL, LFA-1, ITGA
Molecular mass of antigen [kDa]128
Distribution of antigenleukocytes
Entrez Gene ID308995
RRIDAB_2654633, AB_2654634, AB_2654635, AB_2654636, AB_2654637, AB_2654638, AB_2654639, AB_2654640, AB_2654641, AB_2654632

References for CD11a Antibody, anti-rat, REAfinity™

Publications

  1. Tamatani, T. et al. (1991) Characterization of the rat leukocyte integrin, CD11/CD18, by the use of LFA-1 subunit-specific monoclonal antibodies. Eur. J. Immunol. 21(3): 627-633
  2. Tamatani, T. et al. (1991) Molecular mechanisms underlying lymphocyte recirculation. II. Differential regulation of LFA-1 in the interaction between lymphocytes and high endothelial cells. Eur. J. Immunol. 21(3): 855-858

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