Clone:
REA161
Type of antibody:
Recombinant antibodies, Primary antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
IFNGR1, Ifngr, IFN-γRα

Specifications for CD119 Antibody, anti-human, REAfinity™

Overview

Clone REA161 recognizes CD119, the alpha chain subunit of the IFN-γ receptor. CD119 is a 80–100 kDa type I transmembrane protein and is responsible for IFN-γ binding. Along with the β chain, CD119 is also involved in signal transduction via STAT1 activation. Except for mature erythrocytes, expression of CD119 is found on the surface of most human cells.
Additional information: Clone REA161 displays negligible binding to Fc receptors.

Alternative names

IFNGR1, Ifngr, IFN-γRα

Detailed product information

Technical specifications

CloneREA161
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (S), human IgG1
Hostcell line
Type of antibodyRecombinant antibodies, Primary antibodies
Specieshuman
AntigenCD119
Alternative names of antigenIFNGR1, Ifngr, IFN-γRα
Molecular mass of antigen [kDa]53
Distribution of antigenB cells, T cells, dendritic cells, endothelial cells, macrophages
Entrez Gene ID3459
RRIDAB_2857805, AB_2857812, AB_2857802, AB_2654598, AB_2654599, AB_2654604, AB_2654605, AB_2654606, AB_2654607, AB_2654608, AB_2654609, AB_2857815

References for CD119 Antibody, anti-human, REAfinity™

Publications

  1. Harris, D. P. et al. (2005) Regulation of IFN-γ production by B effector 1 cells: Essential roles for T-bet and the IFN-γ receptor. J. Immunol. 174: 6781 -6790
  2. Basler, C. F. et al. (2002) Viruses and the type I interferon antiviral system: induction and evasion. Int. Rev. Immunol. 21(4-5): 305-337

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