Type of antibody:
Primary antibodies, Recombinant antibodies
recombinant human IgG1
Alternative names:
PVRL1, CLPED1, ED4, HV1S, HveC, OFC7, PRR, PVRR, Nectin-1, NECTIN1

Specifications for CD111 Antibody, anti-human, REAfinity™


Clone REA1210 recognizes the human CD111 antigen, a 75 kDa type I transmembrane glycoprotein also known as poliovirus receptor related 1 protein (PRR1), PVRL1, HveC, and Nectin-1. Nectins are involved in the formation of the mechanical adhesive puncta adherentia junctions of synapses. CD111 is an adhesion molecule that can be found in a wide range of tissues where it localizes in various junctions such as the adherens junction of epithelial tissue or the chemical synapse of neurons. In the chemical synapse, CD111 interacts with PVRL3 and both proteins can be found in neuronal tissue already in early stages of brain development as well as in aging brains. CD111 also functions as an entry receptor for herpes simplex virus and pseudorabies virus.
Additional information: Clone REA1210 displays negligible binding to Fc receptors.

Alternative names

PVRL1, CLPED1, ED4, HV1S, HveC, OFC7, PRR, PVRR, Nectin-1, NECTIN1

Detailed product information

Technical specifications

Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (S), human IgG1
Hosthuman cell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Alternative names of antigenPVRL1, CLPED1, ED4, HV1S, HveC, OFC7, PRR, PVRR, Nectin-1, NECTIN1
Molecular mass of antigen [kDa]54
Entrez Gene ID5818
RRIDAB_2811469, AB_2811474, AB_2811470, AB_2811475, AB_2811471, AB_2811476, AB_2811472, AB_2811473

Resources for CD111 Antibody, anti-human, REAfinity™


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References for CD111 Antibody, anti-human, REAfinity™


  1. Cocchi, F. et al. (1998) The V domain of herpesvirus Ig-like receptor (HIgR) contains a major functional region in herpes simplex virus-1 entry into cells and interacts physically with the viral glycoprotein D. Proc. Natl. Acad. Sci. U.S.A. 95(26): 15700-15705
  2. Rikitake, Y. et al. (2012) The role of nectins in different types of cell-cell adhesion. J. Cell. Sci. 125: 3713-3722
  3. Takahashi, K. et al. (1999) Nectin/PRR: an immunoglobulin-like cell adhesion molecule recruited to cadherin-based adherens junctions through interaction with Afadin, a PDZ domain-containing protein. J. Cell Biol. 145(3): 539-549

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