Clone:
REA745
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
ICAM-2, ICAM2

Specifications for CD102 (ICAM-2) Antibody, anti-mouse, REAfinity™

Overview

Clone REA745 recognizes the mouse CD102 antigen, also known as intercellular adhesion molecule 2 (ICAM-2). CD102 is a type I transmembrane glycoprotein belonging to the ICAM proteins of the Ig superfamily. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1. CD102 is found in endothelial cells and leukocytes and is expressed in high level in lung. CD102 plays a role in adhesive interactions, which are important for antigen-specific immune response, in NK-cell mediated clearance, and lymphocyte recirculation. Furthermore, CD102 is involved in other cellular interactions which are important for immune response and surveillance.
Additional information: Clone REA745 displays negligible binding to Fc receptors.

Alternative names

ICAM-2, ICAM2

Detailed product information

Technical specifications

CloneREA745
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse
AntigenCD102 (ICAM-2)
Alternative names of antigenICAM-2, ICAM2
Molecular mass of antigen [kDa]29
Distribution of antigenendothelial cells, NK cells, leukocytes, lung
Entrez Gene ID15896
RRIDAB_2654350, AB_2654351, AB_2654352, AB_2654353, AB_2654354, AB_2654355, AB_2654356, AB_2654349

References for CD102 (ICAM-2) Antibody, anti-mouse, REAfinity™

Publications

  1. Xu, H. et al. (1992) Isolation, characterization, and expression of mouse ICAM-2 complementary and genomic DNA. J. Immunol. 149(8): 2650-2655
  2. Simmons, D. L. (1995) The role of ICAM expression in immunity and disease. Cancer Surv. 24: 144-155
  3. Casasnovas, J. M. et al. (1999) Lymphocyte function-associated antigen-1 binding residues in intercellular adhesion molecule-2 (ICAM-2) and the integrin binding surface in the ICAM subfamily. Proc. Natl. Acad. Sci. U.S.A. 96(6): 3017-3022

Related products for
CD102 (ICAM-2) Antibody, anti-mouse, REAfinity™

2 products available