Clone:
REAL810
Type of antibody:
Releasable fluorochromes, Primary antibodies, Recombinant antibodies
Applications:
MICS, IHC, IF
Alternative names:
bHLHe39, c-Myc, MYCC

Specifications for c-myc Antibody, anti-human, REAdye_lease™

Overview

Clone REAL810 is an antibody fragment derived from the full c-myc antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity.
Clone REAL810 recognizes the multifunctional, nuclear phosphoprotein c-myc, a transcriptional regulator protein, also known as MYC, that is involved in cell cycle progression, apoptosis and cellular transformation. Deregulation including overexpression and mutations of c-myc contributes to the genesis of most human tumors. Expression of c-myc is found in many cancer tissues, e.g. hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma, diffuse large B-cell lymphoma, follicular lymphoma, mantle cell lymphoma, and multiple myeloma.
For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675).

Alternative names

bHLHe39, c-Myc, MYCC

Detailed product information

Technical specifications

CloneREAL810
Clonalitymonoclonal
Isotype controlControl Antibody
Hostcell line
Type of antibodyReleasable fluorochromes, Primary antibodies, Recombinant antibodies
Specieshuman
Antigenc-myc
Alternative names of antigenbHLHe39, c-Myc, MYCC
Distribution of antigenkidney

References for c-myc Antibody, anti-human, REAdye_lease™

Publications

  1. Amati, B. et al. (1994) Myc-Max-Mad: a transcription factor network controlling cell cycle progression, differentiation and death. Curr. Opin. Genet. Dev. : 102-108
  2. Adhikary, S- et al. (2005) Transcriptional regulation and transformation by Myc proteins. Nat. Rev. Mol. Cell Biol. 6(8): 635-645

Seems like you are coming from USA!
Do you want to visit our website in your country?