Clone:
REA1122
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
MICS, IF, IHC
Alternative names:
ANXA1, ANX1, LPC1, Annexin-1, Calpactin II, Calpactin-2, Chromobindin-9, Lipocortin-1

Specifications for Annexin I Antibody, anti-human, REAfinity™

Overview

Clone REA1122 recognizes the human Annexin I anti-inflammatory protein, also known as Calpactin II or Lipocortin-1, which plays an essential role in innate immunity. Annexin I is a Ca
2+
-dependent phospholipid-binding protein, which is found in resting neutrophils, T-cells, extracellular vesicles in blood serum from patients with inflammatory bowel disease, placenta and liver.
Additional information: Clone REA1122 displays negligible binding to Fc receptors.

Alternative names

ANXA1, ANX1, LPC1, Annexin-1, Calpactin II, Calpactin-2, Chromobindin-9, Lipocortin-1

Detailed product information

Technical specifications

CloneREA1122
Clonalitymonoclonal
Isotyperecombinant human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman, other
Cross-reactivitydog
AntigenAnnexin I
Alternative names of antigenANXA1, ANX1, LPC1, Annexin-1, Calpactin II, Calpactin-2, Chromobindin-9, Lipocortin-1
Molecular mass of antigen [kDa]39
Entrez Gene ID301
RRIDAB_2857449, AB_2857450, AB_2857448

References for Annexin I Antibody, anti-human, REAfinity™

Publications

  1. Perretti, M. et al. (2000) Annexin I is stored within gelatinase granules of human neutrophil and mobilized on the cell surface upon adhesion but not phagocytosis. Cell Biol. Int. 24(3): 163-174
  2. Ernst, S. et al. (2004) An annexin 1 N-terminal peptide activates leukocytes by triggering different members of the formyl peptide receptor family. J. Immunol. 172(12): 7669-7676
  3. D'Aquisto, F. et al. (2007) Annexin-1 modulates T-cell activation and differentiation. Blood 109(3): 1095-1102

Seems like you are coming from USA!
Do you want to visit our website in your country?