Clone:
REA931
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
MICS, IF, IHC
Alternative names:
Amyloid fibril protein AA, OC, PIG 4, PIG4, SAA 1, SAA

Specifications for Amyloid A Antibody, anti-human, REAfinity™

Overview

Clone REA931 recognizes the human protein Amyloid A type AA, located in plasma. Amyloid A, an acute phase marker, is an apolipoprotein of the HDL (high-density lipoprotein) complex, which is highly expressed in response to inflammation and tissue injury. Amyloid A increases the export of free cholesterol/phospholipid for reuse in the membranes of several cells, which are neccessary during acute inflammation and repair. REA931 recognizes amyloid deposits in all organs and tissues, also kidney and rectum.
Additional Information: Clone REA931 displays negligible binding to Fc receptors.

Alternative names

Amyloid fibril protein AA, OC, PIG 4, PIG4, SAA 1, SAA

Detailed product information

Technical specifications

CloneREA931
Clonalitymonoclonal
Isotyperecombinant human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenAmyloid A
Alternative names of antigenAmyloid fibril protein AA, OC, PIG 4, PIG4, SAA 1, SAA
RRIDAB_2857406, AB_2857407, AB_2857405

References for Amyloid A Antibody, anti-human, REAfinity™

Publications

  1. Donini, U. et al. (1989) Immunoelectron microscopic classification of amyloid in renal biopsies. J. Histochem. Cytochem. 37(7): 1101-1106
  2. Uhlar, C. M. et al. (1999) Serum amyloid A, the major vertebrate acute-phase reactant. Eur. J. Biochem. 265(2): 501-523
  3. Manley, P. N. et al. (2006) Rapid recycling of cholesterol: the joint biologic role of C-reactive protein and serum amyloid A. Med. Hypotheses 66(4): 784-792

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