Clone:
REA1136
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
MICS, IF, IHC
Alternative names:
TUBA

Specifications for α Tubulin Antibody, anti-human, REAfinity™

Overview

Clone REA1136 recognizes the human, mouse and rat alpha chain of Tubulin (a Tubulin), a heterodimer conisting of homologous but not identical a and b tubulin subunits. Tubulin is a member of the tubulin superfamily, which consists of six members (a, b, g, d, e and z tubulins). Tubulin is expressed by nearly all eukaryotic cells and is an essential part of microtubules, which are involved in a variety of cellular processes. They form the cytoskeleton and play a role in mitosis and meiosis.
Additional information: Clone REA1136 displays negligible binding to Fc receptors.

Alternative names

TUBA

Detailed product information

Technical specifications

CloneREA1136
Clonalitymonoclonal
Isotyperecombinant human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman, mouse, rat, non-human primate, other
Cross-reactivitypig, bovine, dog, chicken, guinea pig, amphibian, gerbil, non-human primate
Antigenα Tubulin
Alternative names of antigenTUBA
Molecular mass of antigen [kDa]50(average of subunits)
Entrez Gene ID7846, 10376, 22142, 22143, 64158, 500929
RRIDAB_2857475, AB_2857476, AB_2857474

References for α Tubulin Antibody, anti-human, REAfinity™

Publications

  1. Nogales, E. et al. (1998) Structure of the alpha beta tubulin dimer by electron crystallography. Nature 391(6663): 199-203
  2. Findeisen, P. et al. (2014) Six subgroups and extensive recent duplications characterize the evolution of the eukaryotic tubulin protein family. Genome Biol. Evol. 6(9): 2274-2288