Clone:
MP6-XT22
Type of antibody:
Primary antibodies, Functional-grade antibodies
Isotype:
rat IgG1, rat IgG1κ
Applications:
FA, ICFC
Alternative names:
TNF, DIF, TNFSF2, Tnfsf1a

Specifications for TNF-α Antibody, anti-mouse

Overview

Mouse tumor necrosis factor α (TNF-α) is secreted by macrophages, monocytes, neutrophils, CD4
+
T cells, and NK cells. It has cytolytic activity against a range of tumor cells and is important in immune regulation. TNF-α binding to surface receptors elicits a wide array of biologic activities, including cytolysis and cytostasis of many tumor cell lines
in vitro
, hemorraghic necrosis of tumors
in vivo
, increased fibroblast proliferation, and enhanced chemotaxis and phagocytosis in neutrophils.

Alternative names

TNF, DIF, TNFSF2, Tnfsf1a

Detailed product information

Technical specifications

CloneMP6-XT22
Clonalitymonoclonal
Isotyperat IgG1κ, rat IgG1
Isotype controlIsotype Control Antibody, rat IgG1
Hostrat
Type of antibodyPrimary antibodies, Functional-grade antibodies
Speciesmouse
AntigenTNF-α
Alternative names of antigenTNF, DIF, TNFSF2, Tnfsf1a
Molecular mass of antigen [kDa]26
Entrez Gene ID21926
RRIDAB_2661140, AB_2661141, AB_2661142, AB_10828341

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TNF-α Antibody, anti-mouse

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