REAlease® CD104 (Integrin β4) Complexes, human

REAlease
®
CD104 (Integrin β4) Complexes
, human

Clone: REAL151 | Dilution: 1:50
Clone REAL151 is an antibody fragment derived from the full CD104 (Integrin β4) antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAlease Complex to bind markers with high avidity.
Clone REAL151 recognizes CD104, which is also known as integrin β4. Integrins are a family of type I transmembrane heterodimeric glycoprotein receptors and exist as non-covalently bound α and β subunits. CD104 interacts with α6 integrin and serves as receptor for laminin and component of hemidesmosomes. Expression of α6β4 integrin is found in the basal aspect of stratified epithelia such as epidermis, stratified squamous epithelium of squamous mucosa, urotheliumin, and certain tumor cells.
The REAlease Kits consist of the respective fluorochrome-conjugated REAlease Complexes and the REAlease Support Kit for removal of the REAlease Complexes and optional relabeling with different fluorochrome-conjugated REAlease Complexes.

Alternative names

Itgb4

Technical specifications

  • Antigen: CD104 (Integrin β4)
  • Clone: REAL151
  • Isotype control: REAL Control
  • Alternative names of antigen: Itgb4
  • Distribution of antigen: epithelial cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, VioBlue, VioGreen
  • Selected references

    1. Tuckwell, D. S. et al. (1993) Integrins: a review of their structure and mechanisms of ligand binding. Symp. Soc. Exp. Biol 47: 107-136
    2. Simon-Assmann, P. et al. (1994) Differential expression of laminin isoforms and alpha 6-beta 4 integrin subunits in the developing human and mouse intestine. Dev. Dyn. 201(1): 71-85
Product options: 8
for 30
tests
(1)
CHF  120.00
for 100
tests
(1)
CHF  290.00
for 30
tests
(1)
CHF  150.00
for 100
tests
(1)
CHF  365.00
for 30
tests
(1)
CHF  150.00
for 100
tests
(1)
CHF  365.00
for 100
tests
(1)
CHF  350.00
for 100
tests
(1)
CHF  420.00

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