CD84 antibodies, human

CD84 antibodies, human

Clone: REA1102 | Dilution: 1:50
Clone REA1102 recognizes the human CD84 antigen, a 65–80 kDa single-chain surface glycoprotein and member of the CD2 subset of the immunoglobulin (Ig) superfamily. CD84 is expressed on granulocytes, monocytes, macrophages, B cells, platelets, antigen-presenting cells, and subsets of T cells including thymocytes and mature T cells. Homophilic ligation of CD84 or ligation with CD84 antibodies has been shown to lead to enhanced proliferation of T cells as well as IFN-γ secretion.
Additional information: Clone REA1102 displays negligible binding to Fc receptors.

Alternative names

Ly9b, SLAMF5, hCD84, GR6

Technical specifications

  • Antigen: CD84
  • Clone: REA1102
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: Ly9b, SLAMF5, hCD84, GR6
  • Entrez Gene ID: 8832
  • Molecular mass of antigen [kDa]: 36
  • Distribution of antigen: B cells, granulocytes, macrophages, monocytes, platelets, T cells, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio615, PE-Vio770, Biotin
  • Selected references

    1. de la Fuente, M. A. et al. (1997) CD84 leukocyte antigen is a new member of the Ig superfamily. Blood 90: 2398-2405
    2. Martin, M. et al. (2001) CD84 functions as a homophilic adhesion molecule and enhances IFN-γ secretion: adhesion is mediated by Ig-like domain 1. J. Immunol. 167: 3668-3676
    3. Tangye, S. G. et al. (2003) Functional requirements for interactions between CD84 and Src homology 2 domain-containing proteins and their contribution to human T cell activation. J. Immunol. 171: 2485-2495
    4. Zaiss, M. et al. (2003) CD84 expression on human hematopoietic progenitor cells. Exp. Hematol. 31: 798-805
Product options: 12
130-119-211

CD84-FITC, human

for 30
tests
(1)
CHF  100.00
130-119-034

CD84-FITC, human

for 100
tests
(1)
CHF  245.00
130-119-212

CD84-PE, human

for 30
tests
(1)
CHF  120.00
130-119-035

CD84-PE, human

for 100
tests
(1)
CHF  290.00
130-119-213

CD84-APC, human

for 30
tests
(1)
CHF  120.00
130-119-036

CD84-APC, human

for 100
tests
(1)
CHF  290.00
for 30
tests
(1)
CHF  130.00
for 100
tests
(1)
CHF  315.00
for 30
tests
(1)
CHF  130.00
for 100
tests
(1)
CHF  315.00
for 30
tests
(1)
CHF  100.00
for 100
tests
(1)
CHF  245.00

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