CD43 antibodies, human

CD43 antibodies, human

Clone: DF-T1 | Dilution: 1:50
Human CD43 (leukosialin) is a cell surface sialoglycoprotein that is involved in cell adhesion, differentiation and activation. The CD43 antigen is expressed on most leukocytes, i.e., T cells, NK cells, granulocytes, monocytes, and macrophages, on hematopoietic stem cells, and on platelets, but not on erythrocytes. Among B cells, CD43 is expressed on activated B cells and plasma cells but not on resting B cells, e.g., naive B cells. In bone marrow, CD43 is found on pro-B cells but is down-regulated during transition to the pre-B cell stage. CD43 is expressed on different myeloid and lymphoid tumors, including some B cell malignancies.

Alternative names

Spn, Leukosialin, GALGP, gpL115, Lsn

Technical specifications

  • Antigen: CD43
  • Clone: DF-T1
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: Spn, Leukosialin, GALGP, gpL115, Lsn
  • Entrez Gene ID: 6693
  • Molecular mass of antigen [kDa]: 38
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    olive baboon (
    Papio anubis
    )
  • Distribution of antigen: B cells, basophils, bone marrow, granulocytes, lymphocytes, macrophages, megakaryocytes, mesenchymal stem cells, monocytes, neutrophils, NK cells, plasma cells, platelets, red blood cells, T cells, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: APC-Vio770
  • Selected references

    1. Stross, W. P. et al. (1989) Molecule detected in formalin fixed tissue by antibodies MT1, DF-T1, and L60 (Leu-22) corresponds to CD43 antigen. J. Clin. Pathol. 42: 953-961
Product options: 2
for 30
tests
(1)
CHF  130.00
for 100
tests
(1)
CHF  315.00

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