CD41b antibodies, human

CD41b antibodies, human

Clone: REA336 | Dilution: 1:11
Clone REA336 recognizes the human CD41b antigen, the β chain of integrin α-IIb (CD41). CD41 associates with CD61 to form the heterodimeric GPIIb/GPIIIa complex that is present on human megakaryocytes and platelets. The CD41/CD61 complex is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin, as well as vitronectin and mediates platelets aggregation.
Additional information: Clone REA336 displays negligible binding to Fc receptors.

Alternative names

ITGA2B, BDPLT16, BDPLT2, GP2B

Technical specifications

  • Antigen: CD41b
  • Clone: REA336
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: ITGA2B, BDPLT16, BDPLT2, GP2B
  • Entrez Gene ID: 3674
  • Molecular mass of antigen [kDa]: 110
  • Distribution of antigen: megakaryocytes, platelets
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio770, APC-Vio770, Biotin
  • Selected references

    1. Corbel, C. et al. (2005) (alpha)IIb integrin, a novel marker for hemopoietic progenitor cells. Int. J. Dev. Biol. 49(2-3): 279-284
    2. Gekas, C. et al. (2013) CD41 expression marks myeloid-biased adult hematopoietic stem cells and increases with age. Blood 121(22): 4463-4472
    3. Poncz, M. et al. (1987) Structure of the platelet membrane glycoprotein IIb. Homology to the alpha subunits of the vitronectin and fibronectin membrane receptors. J. Biol. Chem. 262(18): 8476-8482
Product options: 12
for 30
tests
(1)
CHF  100.00
for 100
tests
(1)
CHF  245.00
130-105-071

CD41b-PE, human

for 30
tests
(1)
CHF  120.00
130-105-041

CD41b-PE, human

for 100
tests
(1)
CHF  290.00
130-105-072

CD41b-APC, human

for 30
tests
(1)
CHF  120.00
130-105-042

CD41b-APC, human

for 100
tests
(1)
CHF  290.00
for 30
tests
(1)
CHF  130.00
for 100
tests
(1)
CHF  315.00
for 30
tests
(1)
CHF  130.00
for 100
tests
(1)
CHF  315.00
for 30
tests
(1)
CHF  100.00
for 100
tests
(1)
CHF  245.00

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