CD253 antibodies, mouse

CD253 antibodies, mouse

Clone: REA1030 | Dilution: 1:50
Clone REA1030 recognizes the mouse CD253 antigen, a type 2 transmembrane protein also known as TNF-related apoptosis-inducing ligand (TRAIL), APO-2 ligand (APO-2L), or TNF ligand superfamily member 10 (TNFSF10). CD253 is expressed on a variety of cells of the innate and adaptive immune system, including natural killer (NK) cells. Often expression is induced or upregulated upon activation. CD253 can trigger apoptosis through trimerization of death receptor DR5 (TRAILR).
Additional information: Clone REA1030 displays negligible binding to Fc receptors.

Alternative names

TNFSF10, APO2L, Ly81, TL2, TRAIL

Technical specifications

  • Antigen: CD253
  • Clone: REA1030
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: TNFSF10, APO2L, Ly81, TL2, TRAIL
  • Entrez Gene ID: 22035
  • Molecular mass of antigen [kDa]: 33
  • Distribution of antigen: B cells, dendritic cells, monocytes, NK cells, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: Biotin, PE, APC, VioBlue, PE-Vio615, PE-Vio770, APC-Vio770, PerCP-Vio700, VioBright 515, FITC
  • Selected references

    1. Wiley, S. R. et al. (1995) Identification and characterization of a new member of the TNF family that induces apoptosis. Immunity 3(6): 673-682
    2. Hofmann, K. (1999) The modular nature of apoptotic signaling proteins. Cell. Mol. Life Sci. 55(8-9): 1113-1128
    3. Locksley, R. M. et al. (2001) The TNF and TNF receptor superfamilies: integrating mammalian biology. Cell 104(4): 487-501
Product options: 17
30 µg in 200 µL (1)
CHF  45.00
130-117-560

CD253-PE, mouse

30 µg in 200 µL (1)
CHF  85.00
130-117-411

CD253-PE, mouse

150 µg in 1 mL (1)
CHF  250.00
130-117-561

CD253-APC, mouse

30 µg in 200 µL (1)
CHF  85.00
130-117-412

CD253-APC, mouse

150 µg in 1 mL (1)
CHF  250.00
30 µg in 200 µL (1)
CHF  105.00
150 µg in 1 mL (1)
CHF  305.00
30 µg in 200 µL (1)
CHF  110.00
150 µg in 1 mL (1)
CHF  325.00
30 µg in 200 µL (1)
CHF  110.00
150 µg in 1 mL (1)
CHF  325.00
30 µg in 200 µL (1)
CHF  110.00
30 µg in 200 µL (1)
CHF  110.00
30 µg in 200 µL (1)
CHF  160.00
150 µg in 1 mL (1)
CHF  460.00
30 µg in 200 µL (1)
CHF  45.00
150 µg in 1 mL (1)
CHF  130.00

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